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Rozerem Side Effects

Generic name: ramelteon

Medically reviewed by Last updated on May 26, 2023.

Note: This document contains side effect information about ramelteon. Some dosage forms listed on this page may not apply to the brand name Rozerem.

Applies to ramelteon: oral tablet.

Serious side effects of Rozerem

Along with its needed effects, ramelteon (the active ingredient contained in Rozerem) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Other side effects of Rozerem

Some side effects of ramelteon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to ramelteon: oral tablet.


Common (1% to 10%): Exacerbated insomnia

Frequency not reported: Behavioral changes, complex behaviors, amnesia, hallucinations, anxiety[Ref]

Nervous system

Common (1% to 10%): Somnolence, dizziness[Ref]


Rare (less than 0.1%): Severe anaphylactic and anaphylactoid reactions (e.g., angioedema)[Ref]


Common (1% to 10%): Nausea[Ref]


Common (1% to 10%): Fatigue[Ref]


1. Product Information. Rozerem (ramelteon). Takeda Pharmaceuticals America. 2005.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.