Raxar Side Effects

Generic Name: grepafloxacin

Note: This page contains side effects data for the generic drug grepafloxacin. It is possible that some of the dosage forms included below may not apply to the brand name Raxar.

Applies to grepafloxacin: oral tablet

Other

Percentages below refer to patients treated on multiple-dose regimens.^[Ref]

Gastrointestinal

Nausea and taste perversion (e.g. medicinal taste) are the most common adverse effects of grepafloxacin (the active ingredient contained in Raxar) occurring in as many as 11% to 16%, and 9% to 18% of patients, respectively. Other gastrointestinal effects including diarrhea, abdominal pain, vomiting, dyspepsia, anorexia, dry mouth, and constipation have been reported in 1% to 4% of patients. Abnormal stools, cheilitis, dysphagia, eructation, flatulence, gastritis, gastrointestinal disorder, gingivitis, glossitis, increased appetite, melena, mouth ulceration, oral moniliasis, rectal disorder, rectal hemorrhage, stomatitis, tenesmus, thirst, tongue discoloration, tongue disorder, and tongue edema have been reported in less than 1% of patients.^[Ref]

Nervous system

Nervous system side effects have included headache, dizziness, insomnia, somnolence, and nervousness in 1% to 5% of patients. Abnormal dreams, abnormal gait, agitation, anxiety, confusion, depression, emotional lability, hallucinations, hyperkinesia, hypoesthesia, hypokinesia, paresthesia, speech disorder, stupor, thinking abnormality, tremor, and vertigo have been reported in less than 1% of patients.^[Ref]

Genitourinary

Genitourinary side effects have included vaginitis and leukorrhea in up to 3% of patients. Albuminuria, balanitis, dysuria, hematuria, impotence, polyuria, urethral pain, uricaciduria, urinary frequency, urinary tract disorder, impaired urination, urine abnormality, and vulvovaginal disorder have been reported in less than 1% of patients.^[Ref]

Dermatologic

Dermatologic side effects have included pruritus and rash in 1% to 2% of treated patients. Acne, alopecia, dry skin, epidermal necrolysis, exfoliative dermatitis, fungal dermatitis, herpes simplex, macropapular rash, skin disorder, sweating, urticaria, and vesiculobullous rash have been reported in less than 1% of patients.^[Ref]

General

Non-specific side effects have included asthenia and pain in 1% to 2% of treated patients. Back pain, body odor, chest pain, chills, facial edema, fever, malaise, neck rigidity, and pelvic pain have been reported in less than 1% of treated patients.^[Ref]

Cardiovascular

Cardiovascular side effects have included arrhythmia, hypotension, palpitations, peripheral vascular disorder, postural hypotension, syncope, tachycardia, and vasodilation in less than 1% of patients.^[Ref]

Hematologic

Hematologic side effects have been reported in less than 1% of patients and have included anemia, eosinophilia, hypochromic anemia, leukocytosis, leukopenia, lymphadenopathy, lymphocytosis, lymphoma-like reaction, decrease in prothrombin, increase in prothrombin, reticuloendothelial hyperplasia, thrombocytopenia, and increased thromboplastin.^[Ref]

Metabolic

Metabolic side effects have included dehydration, edema, electrolyte abnormality, gout, hyperglycemia, hyperlipidemia, hypernatremia, hyperuricemia, peripheral edema, and weight loss in less than 1% of patients.^[Ref]

Musculoskeletal

Musculoskeletal side effects have been reported in less than 1% of patients and have included arthralgia and myalgia.^[Ref]

Respiratory

Respiratory side effects have included asthma, atelectasis, bronchitis, dyspnea, epistaxis, hemoptysis, increased cough, laryngismus, pharyngitis, pleural effusion, rhinitis, and increased sputum in less than 1% of patients.^[Ref]

Ocular

Ocular side effects have included amblyopia, conjunctivitis, dry eyes, eye pain, lacrimation disorder, and photophobia in less than 1% of patients.^[Ref]

Other

Deafness, ear disorder, parosmia, taste loss and tinnitus have been reported in less than 1% of patients.^[Ref]

Hepatic

Hepatic side effects have included abnormal liver function tests in greater than 1% of patients.^[Ref]

It is possible that some side effects of Raxar may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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