Prednisolone ophthalmic Side Effects

For the Consumer

Applies to prednisolone ophthalmic: ophthalmic ointment, ophthalmic solution, ophthalmic suspension

Side effects include:

Elevated IOP, transient stinging or burning, blurred vision, ocular irritation, foreign body sensation.

For Healthcare Professionals

Applies to prednisolone ophthalmic: ophthalmic solution, ophthalmic suspension

Ocular

Ocular side effects have included elevation of intraocular pressure with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.

Corticosteroid containing preparations have been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis.

Bacterial, fungal, and viral secondary ocular infections, transient burning and stinging upon instillation, other minor symptoms of ocular irritation, and visual disturbance (blurry vision) have also been reported.^[Ref]

Hypersensitivity

Hypersensitivity reactions may occur due to the sodium bisulfite preservative, including anaphylactic symptoms and varying degrees of asthmatic episodes. Asthmatic patients may have a higher frequency of allergic reactions than non-asthmatic patients.^[Ref]

Endocrine

Endocrine side effects have included rare cases of systemic hypercorticoidism associated with the use of topical steroids.^[Ref]

Immunologic

Immunologic side effects have included the development of secondary ocular infections with prolonged use.^[Ref]

It is possible that some side effects of prednisolone ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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