Prednisolone ophthalmic Side Effects
For the Consumer
Applies to prednisolone ophthalmic: ophthalmic ointment, ophthalmic solution, ophthalmic suspension
Side effects include:
Elevated IOP, transient stinging or burning, blurred vision, ocular irritation, foreign body sensation.
For Healthcare Professionals
Applies to prednisolone ophthalmic: ophthalmic solution, ophthalmic suspension
General
While the exact frequency of the reported side effects is unknown, the manufacturer reports the following in decreasing order of frequency: elevation of intraocular pressure with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.[Ref]
Ocular
Rare (less than 0.1%): Filtering bleb
Frequency not reported: Intraocular pressure increased, glaucoma, optic nerve damage, posterior subcapsular cataract formation, acute anterior uveitis, perforation of globe, keratitis, conjunctivitis, corneal ulcer, mydriasis, conjunctival hyperemia, ptosis, loss of accommodation, secondary ocular infection developed, visual acuity defect, field defect, transient ocular discomfort, ocular hypertension, scleral/corneal perforation, foreign body sensation, burning, stinging, irritation, vision blurred/impaired, corneal calcification[Ref]
Dermatologic
Frequency not reported: Urticaria, pruritus, rash[Ref]
Immunologic
Frequency not reported: Allergic reaction, anaphylaxis[Ref]
Other
Frequency not reported: Wound healing delayed[Ref]
Nervous system
Frequency not reported: Headache[Ref]
Endocrine
Frequency not reported: Systemic hypercorticoidism[Ref]
Gastrointestinal
Frequency not reported: Dysgeusia[Ref]
References
1. "Product Information. Omnipred (prednisoLONE ophthalmic (prednisolone ophthalmic))." Alcon Laboratories Inc, Fort Worth, TX.
2. "Product Information. Pred Mild (prednisoLONE ophthalmic (prednisolone ophthalmic))." Allergan Inc, Irvine, CA.
3. "Product Information. PrednisoLONE Sodium Phosphate Ophthalmic (prednisoLONE ophthalmic (prednisolone ophthalmic))." Bausch and Lomb, Rochester, NY.
4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
5. Cerner Multum, Inc. "Australian Product Information." O 0
It is possible that some side effects of prednisolone ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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