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Prednisol Side Effects

Generic name: prednisolone ophthalmic

Medically reviewed by Last updated on Jul 14, 2023.

Note: This document contains side effect information about prednisolone ophthalmic. Some dosage forms listed on this page may not apply to the brand name Prednisol.

Applies to prednisolone ophthalmic: ophthalmic solution, ophthalmic suspension.

Serious side effects of Prednisol

Along with its needed effects, prednisolone ophthalmic (the active ingredient contained in Prednisol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking prednisolone ophthalmic:

Incidence not known

Other side effects of Prednisol

Some side effects of prednisolone ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to prednisolone ophthalmic: ophthalmic solution, ophthalmic suspension.


While the exact frequency of the reported side effects is unknown, the manufacturer reports the following in decreasing order of frequency: elevation of intraocular pressure with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.[Ref]


Rare (less than 0.1%): Filtering bleb

Frequency not reported: Intraocular pressure increased, glaucoma, optic nerve damage, posterior subcapsular cataract formation, acute anterior uveitis, perforation of globe, keratitis, conjunctivitis, corneal ulcer, mydriasis, conjunctival hyperemia, ptosis, loss of accommodation, secondary ocular infection developed, visual acuity defect, field defect, transient ocular discomfort, ocular hypertension, scleral/corneal perforation, foreign body sensation, burning, stinging, irritation, vision blurred/impaired, corneal calcification[Ref]


Frequency not reported: Urticaria, pruritus, rash[Ref]


Frequency not reported: Allergic reaction, anaphylaxis[Ref]


Frequency not reported: Wound healing delayed[Ref]

Nervous system

Frequency not reported: Headache[Ref]


Frequency not reported: Systemic hypercorticoidism[Ref]


Frequency not reported: Dysgeusia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2022) "Product Information. Pred Mild (prednisoLONE ophthalmic)." Allergan Inc

4. "Product Information. Omnipred (prednisoLONE ophthalmic)." Alcon Laboratories Inc

5. (2022) "Product Information. PrednisoLONE Sodium Phosphate Ophthalmic (prednisoLONE ophthalmic)." Bausch and Lomb Americas, Inc.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.