Plasma Protein Fraction Side Effects

Medically reviewed by Drugs.com. Last updated on Jul 22, 2024.

Applies to plasma protein fraction: parenteral solution for injection.

Side effects include:

Flushing, urticaria, nausea, headache, back pain.

For healthcare professionals

Applies to plasma protein fraction: intravenous solution.

Cardiovascular adverse events

• Very rare (less than 0.01%): Cardiac arrest, arrhythmia, tachycardia, thromboembolism, hypotension, hypertension, circulatory overload, circulatory collapse, flushing
• Frequency not reported: Severe hypotension, chest pain, chest discomfort^[Ref]

Dermatologic

• Common (1% to 10%): Urticaria, pruritus
• Very rare (less than 0.01%): Rash (erythematous), hyperhidrosis^[Ref]

Gastrointestinal

• Uncommon (0.1% to 1%): Nausea, vomiting
• Very rare (less than 0.01%): Abdominal pain^[Ref]

Musculoskeletal

• Very rare (less than 0.01%): Back pain^[Ref]

Nervous system

• Uncommon (0.1% to 1%): Hypoesthesia
• Very rare (less than 0.01%): Dizziness, paresthesia
• Frequency not reported: Headache^[Ref]

Hematologic

• Very rare (less than 0.01%): Hemolytic anemia, hemorrhagic diathesis, citrate toxicity
• Frequency not reported: Hyperfibrinolysis^[Ref]

Hypersensitivity

• Uncommon (0.1% to 1%): Anaphylaxis
• Rare (less than 0.1%): Hypersensitivity^[Ref]

Local

• Very rare (less than 0.01%): Application site reaction^[Ref]

Metabolic

• Frequency not reported: Alkalosis^[Ref]

Psychiatric

• Very rare (less than 0.01%): Anxiety, agitation, restlessness^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Hypoxia
• Very rare (less than 0.01%): Respiratory failure, pulmonary hemorrhage, bronchospasm, pulmonary edema, dyspnea, respiratory disorder, oxygen saturation decreased
• Frequency not reported: Tachypnea^[Ref]

Other

• Uncommon (0.1% to 1%): Pyrexia
• Very rare (less than 0.01%): Chills, localized edema, malaise, antibody test positive^[Ref]

See also:

Further information

Plasma protein fraction side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

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