Nedocromil Side Effects
Applies to nedocromil: inhalation aerosol with adapter
Gastrointestinal
Gastrointestinal side effects have included unpleasant taste which was reported in approximately 13% of patients receiving nedocromil and resulted in drug withdrawal in up to 3%. Less commonly, nedocromil has caused nausea and vomiting (2% to 4%).[Ref]
Respiratory
Throat irritation may be relieved by drinking water before and after inhalation of nedocromil. Use of a beta-2 agonist prior to nedocromil inhalation may relieve cough and bronchospasm.[Ref]
Respiratory side effects have included cough and throat irritation in 6% to 7% of patients treated with nedocromil. Bronchospasm has been induced in 5% of patients.[Ref]
Nervous system
Nervous system side effects have included headache in up to 6% of patients treated. Less commonly dizziness has been reported.[Ref]
Hepatic
Hepatic side effects have included elevations of liver function tests (SGPT) in approximately 3% of patients treated with nedocromil.[Ref]
Medically reviewed by Drugs.com. Last updated on Nov 17, 2020.
More about nedocromil
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Drug class: mast cell stabilizers
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References
1. Dejong JW, Teengs JP, Postma DS, Vandermark TW, Koeter GH, Demonchy JGR "Nedocromil sodium versus albuterol in the management of allergic asthma." Am J Respir Crit Care Med 149 (1994): 91-7
2. "Product Information. Tilade (nedocromil)." Rhone-Poulenc Rorer, Collegeville, PA.
3. Gonzalez JP, Brogden RN "Nedocromil sodium. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of reversible obstructive airways disease." Drugs 34 (1987): 560-77
4. Rebuck AS, Kesten S, Boulet LP, Cartier A, Cockcroft D, Gruber J, Laberge F, Lee-Chuy E, Keshmiri M, MacDonald GF, et al "A 3-month evaluation of the efficacy of nedocromil sodium in asthma: a randomized, double-blind, placebo-controlled trial of nedocromil sodium conducted by a Canadian multicenter study group." J Allergy Clin Immunol 85 (1990): 612-7
5. Brogden RN, Sorkin EM "Nedocromil sodium. An updated review of its pharmacological properties and therapeutic efficacy in asthma." Drugs 45 (1993): 693-715
6. Parish RC, Miller LJ "Nedocromil sodium." Ann Pharmacother 27 (1993): 599-606
7. Foulds RA "An overview of human safety data with nedocromil sodium." J Allergy Clin Immunol 92 (1993): 202-4
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.