Mesoridazine Side Effects

Applies to mesoridazine: injectable solution, oral concentrate, oral tablet.

If you experience any of the following serious side effects, stop taking mesoridazine and seek emergency medical treatment:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs;

• fever;

• muscle rigidity;

• muscle spasms of the face or neck;

• sweating;

• irregular pulse;

• fast or irregular heartbeats.

• severe restlessness or tremor;

• severe drowsiness;

• blurred vision;

• dizziness or fainting; or

• a rash.

Other, less serious side effects may be more likely to occur. Continue to take mesoridazine and talk to your doctor if you experience:

• dry mouth or stuffy nose;

• constipation;

• mild restlessness, drowsiness, or tremor;

• difficult urination or dark urine;

• decreased sex drive;

• increased appetite; or

• menstrual irregularities or swollen breasts.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

See also:

For healthcare professionals

Applies to mesoridazine: injectable solution, oral concentrate, oral tablet.

Cardiovascular adverse events

Cardiovascular side effects including hypotension and tachycardia have been reported. Mesoridazine has also been reported to prolong the QTc interval in a dose related manner.^[Ref]

Drugs with the potential to prolong the QTc interval have been associated with torsades de pointes-type arrhythmias and sudden death.^[Ref]

Nervous system

Central nervous system side effects including drowsiness, Parkinson's syndrome, dizziness, weakness, tremor, restlessness, ataxia, dystonia, rigidity, slurring, akathisia, and motoric reactions (opisthotonos) have been reported. Autonomic nervous system effects including dry mouth, nausea and vomiting, fainting, stuffy nose, photophobia, constipation, and blurred vision have also been reported.^[Ref]

Adverse effects including rigidity and motoric effects tend to occur later in therapy.^[Ref]

Genitourinary

Genitourinary side effects including inhibition of ejaculation, impotence, enuresis, incontinence and priapism have been reported.^[Ref]

Dermatologic

Dermatologic side effects including itching, rash, hypertrophic papillae of the tongue, and angioneurotic edema have been reported.^[Ref]

Further information

Mesoridazine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer