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Luvox CR Side Effects

Generic Name: fluvoxamine

Note: This document contains side effect information about fluvoxamine. Some of the dosage forms listed on this page may not apply to the brand name Luvox CR.

In Summary

Common side effects of Luvox CR include: asthenia, diarrhea, drowsiness, nausea, headache, and anorexia. Other side effects include: anorgasmia, tremor, diaphoresis, and ecchymoses. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to fluvoxamine: oral capsule extended release, oral tablet

Along with its needed effects, fluvoxamine (the active ingredient contained in Luvox CR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fluvoxamine:

Less common
  • Behavior, mood, or mental changes
  • trouble with breathing
  • trouble with urinating
  • twitching
Rare
  • Absence of or decrease in body movements
  • agitation
  • blurred vision
  • chills
  • clumsiness or unsteadiness
  • confusion
  • convulsions (seizures)
  • diarrhea
  • fever
  • inability to move the eyes
  • increase in body movements
  • menstrual changes
  • nosebleeds
  • overactive reflexes
  • poor coordination
  • red or irritated eyes
  • redness, tenderness, itching, burning, or peeling of the skin
  • restlessness
  • shivering
  • skin rash
  • sore throat
  • sweating
  • talking or acting with excitement you cannot control
  • trembling or shaking
  • unusual bruising
  • unusual, incomplete, or sudden body or facial movements
  • unusual secretion of milk (in females)
  • weakness

Some side effects of fluvoxamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Change in sexual performance or desire
  • constipation
  • headache
  • trouble sleeping
  • unusual tiredness
Less common
  • Abdominal or stomach pain
  • change in sense of taste
  • decreased appetite
  • feeling of constant movement of self or surroundings
  • frequent urination
  • heartburn
  • increased sweating
  • unusual weight gain or loss

For Healthcare Professionals

Applies to fluvoxamine: oral capsule extended release, oral tablet

Gastrointestinal

Very common (10% or more): Nausea (40%), diarrhea (11%), constipation (10%), dyspepsia (10%)
Common (1% to 10%): Vomiting, flatulence, tooth disorder, dysphagia
Uncommon (0.1% to 1%): Gastrointestinal hemorrhage, melena
Rare (less than 0.1%): Ileus, pancreatitis[Ref]

Nervous system

Very common (10% or more): Headache (22%), somnolence (22%), nervousness (12%), dizziness (11%)
Common (1% to 10%): Tremor, hypertonia, agitation, CNS stimulation, taste perversion, hyperkinesia, myoclonus
Uncommon (0.1% to 1%): Abnormal dreams, akathisia, convulsion, dyskinesia, dystonia, euphoria, extrapyramidal syndrome, twitching
Frequency not reported: Paraesthesia[Ref]

Psychiatric

Very common (10% or more): Insomnia (21%)
Common (1% to 10%): Anxiety, decreased libido, depression, manic depression
Rare (less than 0.1%): Withdrawal syndrome
Frequency not reported: Emotional lability, panic attacks, depersonalization, suicidal ideation[Ref]

Other

Very common (10% or more): Asthenia (14%)
Common (10% or more): Flu syndrome, chills, malaise[Ref]

General

The most commonly reported side effects were nausea, diarrhea, headache, somnolence, asthenia, and insomnia.[Ref]

Cardiovascular

Common (1% to 10%): Palpitations, syncope
Frequency not reported: Tachycardia, bradycardia, postural hypotension
Postmarketing reports: Vasculitis, ventricular tachycardia (including torsades de pointes)[Ref]

Dermatologic

Common (1% to 10%): Sweating
Uncommon (0.1% to 1%): Urticaria
Frequency not reported: Rash
Postmarketing reports: Bullous eruption, Henoch-Schonlein purpura, Stevens-Johnson syndrome, toxic epidermal necrolysis[Ref]

Genitourinary

Common (1% to 10%): Abnormal ejaculation, urinary frequency, impotence, anorgasmia, urinary retention
Uncommon (0.1% to 1%): Hematuria, menorrhagia, vaginal hemorrhage
Rare (less than 0.1%): Hematospermia
Frequency not reported: Dysmenorrhea
Postmarketing reports: Amenorrhea[Ref]

Respiratory

Common (1% to 10%): Upper respiratory infection, dyspnea, yawn
Uncommon (0.1% to 1%): Epistaxis
Rare (less than 0.1%): Hemoptysis, laryngismus
Frequency not reported: Rhinitis, increased cough, epistaxis, sinusitis[Ref]

Endocrine

Frequency not reported: Hyperprolactinemia, galactorrhea[Ref]

Musculoskeletal

Frequency not reported: Leg cramps, myalgia, arthralgia[Ref]

Hematologic

Uncommon (0.1% to 1%): Anemia, ecchymosis
Rare (less than 0.1%): Purpura
Frequency not reported: Ecchymosis
Postmarketing reports: Agranulocytosis, aplastic anemia[Ref]

Metabolic

Common (1% to 10%): Anorexia, weight gain, weight loss
Postmarketing reports: Porphyria
Frequency not reported: Thirst[Ref]

Ocular

Common (1% to 10%): Amblyopia
Uncommon (0.1% to 1%): Photosensitivity
Frequency not reported: Visual disturbances (including abnormal or blurred vision), glaucoma[Ref]

Renal

Postmarketing reports: Renal failure[Ref]

Hypersensitivity

Frequency not reported: Anaphylaxis
Postmarketing reports: Angioedema[Ref]

Hepatic

Postmarketing reports: Hepatitis[Ref]

References

1. "Product Information. Luvox (fluvoxamine)." Solvay Pharmaceuticals Inc, Marietta, GA.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of Luvox CR may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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