Loniten Side Effects
Generic name: minoxidil
Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.
Note: This document contains side effect information about minoxidil. Some dosage forms listed on this page may not apply to the brand name Loniten.
Applies to minoxidil: oral tablets.
- Risk of developing potentially serious cardiac effects.110 b (See Cardiovascular Effects under Cautions.) Pericardial effusion, progressing to tamponade may occur and angina pectoris may be exacerbated.110 b Reserve for hypertensive patients who do not respond to maximum therapeutic doses of a diuretic and 2 other antihypertensive agents.110 b
- In animal studies, minoxidil caused myocardial lesions and other adverse cardiac effects.110 b
- Administer under close supervision, usually concomitantly with a β-adrenergic blocking agent (β-blocker) and a diuretic, usually a loop diuretic, to prevent adverse effects.110 b
- Hospitalize and monitor patients with malignant hypertension or those already receiving concomitant guanethidine therapy to prevent too rapid or severe orthostatic decreases in BP.110 b
Side effects include:
Hypertrichosis, salt and water retention, pericardial effusion, nausea, vomiting.
For Healthcare Professionals
Applies to minoxidil: compounding powder, oral tablet.
Most patients receiving have experienced a decrease of preexisting adverse medical events attributable to their disease or previous therapy. The most frequently reported side effects were hypertrichosis, tachycardia, pericarditis, and an abnormal ECG.[Ref]
Very common (10% or more): ECG abnormal (up to 60%), tachycardia, pericarditis
Common (1% to 10%): Pericardial effusion, tamponade
Frequency not reported: Angina pectoris, hypotension[Ref]
Very common (10% or more): Hypertrichosis (up to 80%), hair color changed
Rare (less than 0.1%): Stevens-Johnson syndrome, dermatitis bullous, rash
Frequency not reported: Toxic epidermal necrolysis[Ref]
Elongation, thickening, and enhanced pigmentation of fine body hair has been reported in about 80% of patients. This usually develops within 3 to 6 weeks after beginning therapy and is first noticed on the temples, between the eyebrows, between the hairline and the eyebrows, or in the sideburn area of the upper lateral cheek, and eventually extending to the back, arms, legs, and scalp. Upon discontinuation of this drug, new hair growth stops, however, 1 to 6 months may be required for restoration to pretreatment appearance. Endocrine abnormalities have not been found to explain the abnormal hair growth.[Ref]
Common (1% to 10%): Gastrointestinal disorder
Frequency not reported: Nausea/vomiting, gastrointestinal intolerance[Ref]
Rare (less than 0.1%): Leukopenia, thrombocytopenia
Frequency not reported: Hematocrit decreased, hemoglobin decreased, erythrocyte count decreased
Common (1% to 10%): Fluid retention[Ref]
Uncommon (0.1% to 1%): Breast tenderness[Ref]
Uncommon (0.1% to 1%): Pleural effusion
Common (1% to 10%): Edema
Frequency not reported: Peripheral edema, weight gain, blood creatinine increased, blood urea increased, alkaline phosphatase increased[Ref]
More about Loniten (minoxidil)
- Check interactions
- Drug images
- Dosage information
- During pregnancy
- Drug class: vasodilators
- En español
Related treatment guides
1. "Product Information. Loniten (minoxidil)." Pharmacia and Upjohn (2002):
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.