Minoxidil use while Breastfeeding
Drugs containing Minoxidil: Rogaine, Loniten, Rogaine Women's, Hair Regrowth Treatment for Men, Rogaine Men's Extra Strength, Hair Regrowth Treatment for Women, Ronoxidil, Rogaine Extra Strength
Medically reviewed on Dec 31, 2018
Minoxidil Levels and Effects while Breastfeeding
Summary of Use during Lactation
Because of the minimal amount of information on this potent agent, use minoxidil with caution, particularly when therapy involves a large maternal dosage or breastfeeding a newborn. Topical minoxidil should pose low risk to the breastfed infant.
Maternal Levels. In one case report, a 2-month-postpartum mother who was taking minoxidil 5 mg twice daily was given a, oral dose of 7.5 mg. The peak milk level of minoxidil plus glucuronide conjugate was 45.1 mcg/L at 1 hour after the dose. Milk levels paralleled serum levels, falling rapidly after the first hour to a concentration of 12.4 mcg/L at 3 hours, 4 mcg/L at 6 hours, 1.9 mcg/L at 9 hours, 0.8 mcg/L at 12 hours after the dose.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
No hypertrichosis or other abnormal signs were seen in one infant breastfed for 2 months of maternal minoxidil therapy.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
1. Valdivieso A, Valdes G, Spiro TE et al. Minoxidil in breast milk. Ann Intern Med. 1985;102:135. Letter. PMID: 3966734
CAS Registry Number
LactMed Record Number
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