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Generic name: minoxidilmin-OX-i-dil ]
Drug class: Vasodilators

Medically reviewed by on Aug 9, 2023. Written by Cerner Multum.

What is Loniten?

Loniten is a vasodilator that relaxes (widens) blood vessels and improves blood flow.

Loniten is used to treat severely high blood pressure (hypertension) that is causing symptoms or damaging your vital organs. This medicine is usually given together with two other medicines to help prevent serious side effects.

Loniten tablets should not be used to promote scalp hair growth. Only the topical form of minoxidil (Rogaine) is recommended for that use.

Loniten may also be used for purposes not listed in this medication guide.

Loniten side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Loniten may cause serious side effects. Call your doctor at once if you have:

Common side effects of Loniten may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


You should not use Loniten if you have pheochromocytoma (adrenal gland tumor).

Loniten is usually given together with two other medicines to help prevent serious side effects. Use all medications as directed by your doctor.

Call your doctor at once if you have new or worsening chest pain, shortness of breath (even while lying down), pain when you breathe, or fast heartbeats.

Before taking this medicine

You should not use Loniten if you are allergic to it, or if you have:

To make sure Loniten is safe for you, tell your doctor if you have:

It is not known whether this medicine will harm an unborn baby. However, a newborn baby could have excessive hair growth if the mother has taken Loniten during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Minoxidil can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Do not give this medicine to a child without medical advice.

How should I take Loniten?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use Loniten in larger or smaller amounts or for longer than recommended.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to quickly treat any serious side effects that occur.

Read all patient information, medication guides, and instruction sheets provided to you. Do not change your doses or medication schedule without your doctor's advice.

While taking Loniten, you will need to measure your heart rate by checking your pulse. Your doctor or nurse can show you how to check your pulse.

Weigh yourself each day while you are taking Loniten. Call your doctor if you gain more than 5 pounds quickly.

Your blood pressure will need to be checked often. Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG).

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Do not share this medicine with another person, even if they have the same symptoms you have.

Store Loniten at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dizziness or fainting.

What should I avoid while taking Loniten?

You may need to limit or reduce the salt in your diet while taking Loniten. Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Ask your doctor or pharmacist before taking a cough or cold medicine that contains a decongestant such as phenylephrine.

What other drugs will affect Loniten?

Other drugs may interact with minoxidil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Popular FAQ

Topical minoxidil (Rogaine) appears to be effective for enhancing beards and stimulating hair growth in the lower facial region, although few studies have been reported. One trial found a significant improvement in beard growth as assessed by photography, as well as significant improvements in facial hair count after 16 weeks of twice daily topical minoxidil 3%. The participants in the trial also reported noticing that their beard growth had improved. There was no difference noted between the thickness of beard hairs in those who applied minoxidil compared to those who applied a placebo (an inactive) treatment. Continue reading

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.