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Liquadd Side Effects

Generic name: dextroamphetamine

Medically reviewed by Drugs.com. Last updated on Sep 14, 2022.

Note: This document contains side effect information about dextroamphetamine. Some dosage forms listed on this page may not apply to the brand name Liquadd.

Applies to dextroamphetamine: oral conventional tablets, oral extended-release capsules, oral fixed-combination conventional tablets and extended-release capsules.

Warning

    Abuse Potential
  • Amphetamines have a high potential for abuse.101 102 103

  • Administration of amphetamines for prolonged periods of time may lead to drug dependence.101 102 103 b

  • Particular attention should be paid to the possibility of individuals obtaining amphetamines for nontherapeutic use or distribution to others, and the drugs should be prescribed or dispensed sparingly.101 102 103

  • The possibility that family members may abuse the patient’s medication should be considered.e

    Sudden Death and Serious Cardiovascular Events
  • Possible sudden death and serious cardiovascular events, particularly in individuals who abuse amphetamines.101 102 103 h (See Sudden Death and Serious Cardiovascular Events under Cautions.)

Side effects include:

Most commonly abdominal pain (stomachache), loss of appetite, insomnia.

Also, palpitations, tachycardia, elevation of BP, overstimulation, restlessness, dizziness, euphoria, dyskinesia, dysphoria, tremor, headache, dryness of mouth, taste aberration, diarrhea, constipation, abdominal bloating, impotence, changes in libido.

Isolated reports of cardiomyopathy associated with chronic amphetamine use.

Anorexia and weight loss may occur as undesirable effects when amphetamines are used for other than the anorectic effect.

For Healthcare Professionals

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet, transdermal film.

Metabolic

Very common (10% or more): Decreased appetite, reduced weight gain, weight loss

Common (1% to 10%): Anorexia

Frequency not reported: Acidosis[Ref]

Psychiatric

Very common (10% or more): Insomnia, nervousness

Common (1% to 10%): Abnormal behavior, aggression/hostility, excitation, anxiety, depression, irritability

Uncommon (0.1% to 1%): Psychotic episodes/psychosis

Very rare (less than 0.01%): Suicidal behavior (including completed suicide), mania, hallucinations

Frequency not reported: Overstimulation, restlessness, euphoria, dysphoria, confusion, dependence, emotional lability, impaired cognitive test performance, altered libido, night terrors, obsessive-compulsive behavior, panic states, paranoia[Ref]

Cardiovascular

Common (1% to 10%): Arrhythmia, palpitations, tachycardia

Rare (less than 0.1%): Angina pectoris

Very rare (less than 0.01%): Cardiac arrest

Frequency not reported: Blood pressure and heart rate changes (usually elevated), cardiomyopathy, myocardial infarction, chest pain, cardiovascular collapse, Raynaud's phenomenon[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain and cramps, nausea, vomiting, dry mouth

Frequency not reported: Ischemic colitis, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia

Rare (less than 0.1%): Growth retardation

Very rare (less than 0.01%): Muscle cramps

Frequency not reported: Rhabdomyolysis[Ref]

Nervous system

Common (1% to 10%): Vertigo, dyskinesia, headache, hyperactivity

Very rare (less than 0.01%): Tourette syndrome, tics, exacerbation of pre-existing motor and phonic tics, convulsions, choreoathetoid movements, intracranial hemorrhage, cerebral vasculitis and/or occlusion, neuroleptic malignant syndrome (NMS)

Frequency not reported: Dizziness, tremor, ataxia, dysgeusia, concentration difficulties, hyperreflexia, stroke[Ref]

Dermatologic

Rare (less than 0.1%): Rash, urticaria

Very rare (less than 0.01%): Erythema multiforme, exfoliative dermatitis, fixed drug eruption

Frequency not reported: Sweating, alopecia[Ref]

Ocular

Rare (less than 0.1%): Visual accommodation difficulties, blurred vision, mydriasis[Ref]

Other

Rare (less than 0.1%): Fatigue

Frequency not reported: Hyperpyrexia, sudden death[Ref]

Hematologic

Very rare (less than 0.01%): Anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura[Ref]

Hepatic

Very rare (less than 0.01%): Abnormal liver function ranging from hepatic enzyme elevations to hepatic coma[Ref]

Endocrine

Frequency not reported: Impotence, libido changes, frequent or prolonged erections[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions (e.g., angioedema and anaphylaxis)[Ref]

Renal

Frequency not reported: Renal damage[Ref]

Frequently asked questions

More about Liquadd (dextroamphetamine)

Patient resources

Other brands

Dexedrine, Zenzedi, ProCentra, Dextrostat, Xelstrym

Professional resources

Related treatment guides

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Dexedrine (dextroamphetamine)." SmithKline Beecham (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.