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Lemborexant Side Effects

Medically reviewed by Last updated on Oct 3, 2020.

For the Consumer

Applies to lemborexant: oral tablet

Side effects requiring immediate medical attention

Along with its needed effects, lemborexant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lemborexant:

More common

  • Sleepiness or unusual drowsiness
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual tiredness or weakness

Less common

  • Temporary inability to move or talk while you are going to sleep or waking up


  • Changes in behavior
  • discouragement
  • feeling sad or empty
  • irritability
  • lack of appetite
  • loss of interest or pleasure
  • seeing, hearing, or feeling things that are not there
  • thoughts of killing oneself
  • trouble concentrating

Side effects not requiring immediate medical attention

Some side effects of lemborexant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to lemborexant: oral tablet


Common (1% to 10%): Sleep paralysis

Uncommon (0.1% to 1%): Hypnagogic hallucinations

Very rare (less than 0.01%): Complex sleep behaviors[Ref]


Very common (10% or more): Somnolence or fatigue (10%)

Common (1% to 10%): Nightmare or abnormal dreams[Ref]


Common (1% to 10%): Headache[Ref]


1. "Product Information. Dayvigo (lemborexant)." Eisai Inc, Woodcliff Lake, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.