Lemborexant Dosage
Medically reviewed by Drugs.com. Last updated on May 23, 2024.
Applies to the following strengths: 5 mg; 10 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Insomnia
5 mg orally once a day at bedtime
- Maximum dose: 10 mg once at bedtime
Use: For the treatment of patients with insomnia, characterized by difficulties with sleep onset and/or sleep maintenance.
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
Mild liver dysfunction: No adjustment recommended.
Moderate liver dysfunction: Maximum dose 5 mg/day at bedtime
Severe liver dysfunction: Not recommended.
Dose Adjustments
USE WITH STRONG OR MODERATE CYP450 3A4 INHIBITORS: Not recommended.
USE WITH WEAK CYP450 3A4 INHIBITORS: Up to 5 mg orally once a day immediately prior to bedtime
- Maximum dose: 5 mg/day
USE WITH STRONG OR MODERATE CYP450 3A4 INDUCERS: Not recommended.
Precautions
CONTRAINDICATIONS: Patients with narcolepsy
Safety and efficacy have not been established in children.
Consult WARNINGS section for additional precautions.
US Controlled Substance: Schedule IV
Dialysis
Data not available
Other Comments
Administration advice:
- Take immediately before going to bed.
- Dose should be taken with at least 7 hours remaining before the planned time of awakening.
- Time to sleep onset may be delayed if taken with or soon after a meal.
Storage requirements:
- Store at 20C to 25C.
Patient advice:
- Read the approved patient labeling.
- Take only when preparing for or getting into bed and only if you can stay in bed for a full night (at least 7 hours) before being active again.
- The effect of this drug may be delayed if taken with or soon after a meal.
- This drug can impair daytime wakefulness even when used as prescribed. The risk of daytime impairment increases if you do not have a full night of sleep.
- Use caution if you are driving and doing activities requiring complete mental alertness.
- Increased drowsiness may increase your risk of falling.
- This drug may cause complex sleep behaviors, including sleepwalking, sleep-driving, preparing and eating food, making phone calls, or having sex while not being fully awake. Discontinue and notify your healthcare provider immediately if you develop any of these symptoms.
- Report any worsening of depression or suicidal thoughts immediately.
- There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to this drug. Talk to your doctor if you are pregnant.
- Do not consume alcohol while taking this drug.
- Tell your doctor all your medical conditions, and all the other drugs you are taking, with or without a prescription.
- Do not increase the prescribed dose of this drug and inform your doctor if you think the drug "does not work".
Frequently asked questions
More about lemborexant
- Check interactions
- Compare alternatives
- Reviews (294)
- Side effects
- During pregnancy
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
See also:
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Ambien
Ambien (zolpidem) is a prescription sedative used to treat insomnia, helping you fall asleep and ...
Lunesta
Lunesta is a sedative and is used to treat insomnia. Lunesta's effects typically begin within 30 ...
Eszopiclone
Eszopiclone (brand name Lunesta) is a sedative and is used to treat insomnia. Eszopiclone's effects ...
Temazepam
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and ...
Doxepin
Doxepin systemic is used for anxiety, depression, insomnia, irritable bowel syndrome, major ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.