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Intuniv Side Effects

Generic name: guanfacine

Medically reviewed by Drugs.com. Last updated on Apr 24, 2024.

Note: This document provides detailed information about Intuniv.

Applies to guanfacine: oral tablet, oral tablet extended release Side Effects associated with guanfacine. Some dosage forms listed on this page may not apply specifically to the brand name Intuniv.

Applies to guanfacine: oral tablet, oral tablet extended release.

Precautions

Your doctor should check you or your child's progress at regular visits to make sure this medicine is working properly and to decide if you or your child should continue to take it.

You or your child will also need to have your blood pressure and heart rate measured before starting this medicine and while you or your child are using it. If you notice any change to you or your child's recommended blood pressure or heart rate, call your doctor right away. If you have questions about this, talk to your doctor.

Do not suddenly Stop taking guanfacine (the active ingredient contained in Intuniv) without checking first with your doctor. Stopping this medicine suddenly may increase your blood pressure and heart rate (rebound hypertension). Your doctor may want you to slowly reduce the amount you or your child are taking before stopping it completely.

Make sure that you have enough guanfacine on hand to last through the weekends, holidays, and vacations. You should not miss any doses. You may want to ask your doctor for another written prescription for guanfacine to carry in your wallet or purse. You can then have it filled if you run out when you are away from home.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine.

Guanfacine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you or your child are using this medicine.

Guanfacine may cause some people to become dizzy, drowsy, faint, lightheaded, or less alert than they are normally. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Also, standing up slowly when getting up from a lying or sitting position may also help.

This medicine may worsen heart rhythm problems (eg, sinus node dysfunction, atrioventricular block), especially in patients who are taking other medicines. Talk to your doctor if you have concerns.

Guanfacine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your physician or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements.

Serious side effects of Intuniv

Along with its needed effects, guanfacine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking guanfacine:

More common side effects

  • blurred vision
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness

Less common side effects

  • chest pain or discomfort
  • cough
  • difficulty with breathing
  • fast, slow, pounding, or irregular heartbeat
  • increased need to urinate
  • lightheadedness, dizziness, or fainting
  • mental depression
  • noisy breathing
  • passing urine more often
  • tightness in the chest

Incidence not known

  • agitation
  • back pain
  • cracks in the skin
  • drowsiness
  • fast, pounding, or irregular pulse
  • feeling of constant movement of self or surroundings
  • fever
  • headache
  • irritability
  • loss of consciousness
  • loss of heat from the body
  • mood or mental changes
  • numbness or tingling in the arms, legs, or face
  • red, swollen skin
  • scaly skin
  • seeing or hearing things that are not there
  • seizures
  • sensation of spinning
  • stiff neck
  • swelling
  • vomiting
  • weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking guanfacine:

Symptoms of overdose

Other side effects of Intuniv

Some side effects of guanfacine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • constipation
  • dizziness
  • dryness of the mouth
  • nausea
  • sleepiness or unusual drowsiness
  • unusual dullness or feeling of sluggishness
  • upper abdominal or stomach pain
  • weight gain

Less common side effects

  • belching
  • decreased appetite
  • decreased sexual ability
  • dry, itching, or burning eyes
  • heartburn
  • indigestion
  • lack or loss of strength
  • paleness of the skin
  • stomach discomfort, upset, or pain
  • trouble with sleeping

Incidence not known

  • change in taste
  • decreased interest in sexual intercourse
  • difficulty in moving
  • general feeling of discomfort or illness
  • hair loss, thinning of hair
  • inability to have or keep an erection
  • joint pain or swelling
  • leg cramp or pain
  • loss in sexual ability, desire, drive, or performance
  • muscle ache, cramp, pain, or stiffness
  • seeing or hearing things that are not there

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, Check with your doctor immediately if you notice the following side effects:

For healthcare professionals

Applies to guanfacine: oral tablet, oral tablet extended release.

General adverse events

The most common adverse reactions were dry mouth, somnolence, headache, fatigue, dizziness, abdominal pain, constipation, appetite decreased, and sedation.[Ref]

Gastrointestinal

Nervous system

Other

Metabolic

Psychiatric

Cardiovascular

Genitourinary

Dermatologic

Respiratory

Hepatic

Immunologic

Musculoskeletal

Ocular

See also:

References

1. (2001) "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. (2009) "Product Information. Intuniv (guanfacine)." Shire US Inc

Further information

Intuniv side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.