Skip to Content

Imiglucerase Side Effects

For the Consumer

Applies to imiglucerase: intravenous powder for solution

Along with its needed effects, imiglucerase may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of imiglucerase may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Abdominal discomfort
  • decrease in blood pressure, decrease in frequency of urination
  • dizziness
  • headache
  • itching
  • nausea
  • rash

For Healthcare Professionals

Applies to imiglucerase: intravenous powder for injection

General

Experience in patients treated with this drug have revealed that about 13.8% of patients experienced adverse events which were judged to be related to administration and included discomfort, pruritus, burning, swelling, or sterile abscess at the site of venipuncture.[Ref]

Local

Common (1% to 10%): Discomfort, burning, swelling, sterile abscess
Frequency not reported: Pruritus[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, abdominal pain, vomiting, diarrhea
Uncommon (0.1% to 1%): Abdominal cramping[Ref]

Cardiovascular

Common (1% to 10%): Tachycardia
Uncommon (0.1% to 1%): Flushing, hypotension, cyanosis[Ref]

Immunologic

Common (1% to 10%): Hypersensitivity reaction
Rare (less than 0.1%): Anaphylactoid reaction[Ref]

Dermatologic

Common (1% to 10%): Rash, urticaria, pruritus, angioedema[Ref]

Musculoskeletal

Common (1% to 10%): Backache
Uncommon (0.1% to 1%): Arthralgia[Ref]

Respiratory

Common (1% to 10%): Dyspnea, coughing[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Uncommon (0.1% to 1%): Paresthesia[Ref]

Other

Common (1% to 10%): Fatigue, fever, chills
Uncommon (0.1% to 1%): Rigors
Frequency not reported: Chest discomfort, peripheral edema[Ref]

References

1. "Product Information. Cerezyme (imiglucerase)." Genzyme Corporation, Cambridge, MA.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of imiglucerase may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide