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Imiglucerase Dosage

Applies to the following strength(s): 200 units ; 400 units

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Gaucher Disease

Initial dosage: ranges from 2.5 units/kg of body weight 3 times a week to 60 units/kg once every 2 weeks. Imiglucerase for injection is administered by intravenous infusion over 1 to 2 hours.

Dosage should be individualized to each patient. Disease severity may dictate that treatment be initiated at a relatively high dose or relatively frequent administration.

Usual Pediatric Dose for Gaucher Disease

Greater than or equal to 2 years of age:

Initial dosage: ranges from 2.5 units/kg of body weight 3 times a week to 60 units/kg once every 2 weeks. Imiglucerase for injection is administered by intravenous infusion over 1 to 2 hours.

Dosage should be individualized to each patient. Disease severity may dictate that treatment be initiated at a relatively high dose or relatively frequent administration.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Dosage adjustments should be made on an individual basis and may increase or decrease, based on achievement of therapeutic goals as assessed by routine comprehensive evaluations of the patient's clinical manifestations.

Dialysis

Data not available

Other Comments

Sixty units/kg every 2 weeks is the dosage for which the most data are available.

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