Geocillin Side Effects
Generic name: carbenicillin
Note: This document provides detailed information about Geocillin Side Effects associated with carbenicillin. Some dosage forms listed on this page may not apply specifically to the brand name Geocillin.
Applies to carbenicillin: oral tablet.
Important warnings
This medicine can cause some serious health issues
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
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diarrhea that is watery or bloody;
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fever, chills, body aches, flu symptoms;
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easy bruising or bleeding, unusual weakness;
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urinating less than usual or not at all;
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severe skin rash, itching, or peeling;
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agitation, confusion, unusual thoughts or behavior; or
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seizure (black-out or convulsions).
Less serious side effects of carbenicillin (the active ingredient contained in Geocillin) may include:
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nausea, vomiting, stomach pain;
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vaginal itching or discharge;
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headache;
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swollen, black, or "hairy” tongue; or
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thrush (white patches or inside your mouth or throat).
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
For healthcare professionals
Applies to carbenicillin: oral tablet.
Gastrointestinal adverse events
Gastrointestinal side effects have included nausea, vomiting, diarrhea, bad taste, flatulence, glossitis, abdominal cramps, dry mouth, furry tongue, rectal bleeding, anorexia, loose stools, and epigastric distress. Pseudomembranous colitis has been reported rarely.[Ref]
Hypersensitivity
Hypersensitivity reactions have included anaphylaxis, rash, urticaria, pruritus, fever, and eosinophilia.[Ref]
Hematologic
Hematologic side effects have included anemia, thrombocytopenia, leukopenia, neutropenia, and eosinophilia. Carbenicillin (the active ingredient contained in Geocillin) affects platelet aggregation and bleeding may occur.[Ref]
Cardiovascular
Cardiovascular side effects may include congestive heart failure resulting from the sodium content of carbenicillin (the active ingredient contained in Geocillin) [Ref]
Metabolic
Metabolic side effects may include hypokalemia.[Ref]
Hepatic
Hepatic side effects have included mild elevations of liver transaminases.[Ref]
Genitourinary
Genitourinary side effects have included vaginitis.[Ref]
Other
Other side effects have included itchy eyes and headache.[Ref]
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References
1. O'Meara TF, Simmons RA (1980) "Carbenicillin and pseudomembranous enterocolitis." Ann Intern Med, 92, p. 440-1
2. Saadah HA (1980) "Carbenicillin and pseudomembranous enterocolitis." Ann Intern Med, 93, p. 645
3. Huang NN, Palmer J, Keith H, Schidlow D, Braverman S, Goldberg M (1983) "Comparative efficacy and tolerance of azlocillin and carbenicillin in patients with cystic fibrosis: a double blind study." J Antimicrob Chemother, 11, p. 205-14
4. (2002) "Product Information. Geocillin (carbenicillin)." Roerig Division
5. Limbird LE, Gilman AG, eds., Hardman JG (2001) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: McGraw-Hill
More about Geocillin (carbenicillin)
- Check interactions
- Compare alternatives
- Drug images
- Dosage information
- During pregnancy
- Drug class: antipseudomonal penicillins
Related treatment guides
Further information
Geocillin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.