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Floxin Otic Side Effects

Generic Name: ofloxacin otic

Note: This document contains side effect information about ofloxacin otic. Some of the dosage forms listed on this page may not apply to the brand name Floxin Otic.

For the Consumer

Applies to ofloxacin otic: otic solution

Along with its needed effects, ofloxacin otic (the active ingredient contained in Floxin Otic) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ofloxacin otic:

Less common
  • Burning, itching, redness, skin rash, swelling, or other sign of irritation not present before use of this medicine

Check with your doctor as soon as possible if any of the following side effects occur while taking ofloxacin otic:

Less common Rare

Some side effects of ofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Change in taste
  • earache
  • numbness or tingling

For Healthcare Professionals

Applies to ofloxacin otic: otic solution


Very common (10% or more): Application site reaction (up to 16.8%)[Ref]


Common (1% to 10%): Pruritus, rash
Frequency not reported: Seborrhea, dermatitis, eczema, erythematous rash, follicular rash, flushing, urticaria[Ref]

Nervous system

Common (1% to 10%): Paresthesia, dizziness
Uncommon (0.1% to 1%): Headache, vertigo
Frequency not reported: Tremor, hypoesthesia, dysesthesia, hyperkinesia[Ref]


Common (1% to 10%): Taste perversion
Uncommon (0.1% to 1%): Diarrhea, nausea, vomiting, dry mouth
Frequency not reported: Dyspepsia, abdominal pain, halitosis[Ref]


Uncommon (0.1% to 1%): Earache, otorrhagia, tinnitus, fever
Frequency not reported: Transient loss of hearing, otitis externa, otitis media, inflammation, pain, fungal infection[Ref]


Frequency not reported: Coughing, pharyngitis, rhinitis, sinusitis[Ref]


Frequency not reported: Hypertension, hot flush, tachycardia[Ref]


Frequency not reported: Insomnia
Postmarketing reports: Transient neuropsychiatric disturbances[Ref]


1. "Product Information. Floxin otic (ofloxacin otic)." Daiichi Pharmaceuticals, Fort Lee, NJ.

Some side effects of Floxin Otic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.