Skip to main content

Extendryl DM Side Effects

Generic name: chlorpheniramine / dextromethorphan / methscopolamine

Note: This document contains side effect information about chlorpheniramine / dextromethorphan / methscopolamine. Some dosage forms listed on this page may not apply to the brand name Extendryl DM.

Applies to chlorpheniramine/dextromethorphan/methscopolamine: oral tablet extended release.


Cardiovascular side effects have included bradycardia, tachycardia, flushing, and, palpitations.[Ref]


Gastrointestinal side effects have included nausea, xerostomia, diarrhea, abdominal pain, appetite increase, weight gain, constipation, and dysphagia.[Ref]


Ocular side effects have included mydriasis, diplopia, and blurred vision.[Ref]


Musculoskeletal side effects have included arthralgia and weakness.[Ref]

Nervous system

Nervous system side effects have included headache, excitability, irritability, fatigue, nervousness, dizziness, drowsiness, confusion, and memory impairment.[Ref]


Genitourinary side effects have included urinary retention.[Ref]


Renal side effects have included polyuria.[Ref]


Respiratory side effects have included pharyngitis.[Ref]

More about Extendryl DM (chlorpheniramine / dextromethorphan / methscopolamine)

Related treatment guides


1. "Product Information. Extendryl DM (chlorpheniramine/DM/methscopolamine)." Apothecon Inc (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.