Extendryl DM Interactions
There are 479 drugs known to interact with Extendryl DM (chlorpheniramine / dextromethorphan / methscopolamine), along with 21 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 85 are major, 374 are moderate, and 20 are minor.
- View Extendryl DM alcohol/food interactions (3)
- View Extendryl DM disease interactions (21)
Medications known to interact with Extendryl DM
Note: Showing generic names only.
5
A
- abametapir topical
- abiraterone
- abobotulinumtoxinA
- acebutolol
- acetaminophen
- acetylcarbromal
- acetylcholine ophthalmic
- aclidinium
- acrivastine
- adagrasib
- adalimumab
- alefacept
- alfentanil
- allopurinol
- almotriptan
- alprazolam
- amantadine
- ambenonium
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anakinra
- apomorphine
- apraclonidine ophthalmic
- arbutamine
- aripiprazole
- asenapine
- atenolol
- atropine
- azatadine
- azelastine nasal
B
- baclofen
- belladonna
- bendroflumethiazide
- benzgalantamine
- benzphetamine
- benzthiazide
- benztropine
- berotralstat
- betaxolol
- bethanechol
- bimekizumab
- biperiden
- bisoprolol
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- brodalumab
- bromocriptine
- brompheniramine
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- canakinumab
- cannabidiol
- cannabis
- capivasertib
- carbachol ophthalmic
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- celecoxib
- cenobamate
- cetirizine
- cevimeline
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chlorothiazide
- chlorphenesin
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- cimetidine
- cinacalcet
- cisapride
- citalopram
- clemastine
- clidinium
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobicistat
- codeine
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dacomitinib
- danicopan
- dantrolene
- daridorexant
- darifenacin
- daxibotulinumtoxinA
- delavirdine
- demecarium bromide ophthalmic
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexfenfluramine
- dexmedetomidine
- dextroamphetamine
- dezocine
- diazepam
- dicyclomine
- difelikefalin
- digoxin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- disopyramide
- divalproex sodium
- dolasetron
- donepezil
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- duloxetine
E
- echothiophate iodide ophthalmic
- edrophonium
- efavirenz
- elacestrant
- eletriptan
- eliglustat
- eluxadoline
- emapalumab
- entacapone
- epcoritamab
- ergotamine
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethchlorvynol
- ethosuximide
- ethotoin
- ezogabine
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fesoterodine
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosphenytoin
- fostamatinib
- frovatriptan
- furazolidone
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gepirone
- givosiran
- glofitamab
- glycerol phenylbutyrate
- glycopyrrolate
- glycopyrronium topical
- golimumab
- granisetron
- guanfacine
- guanidine
- guselkumab
H
- halazepam
- halofantrine
- haloperidol
- heroin
- histamine phosphate
- house dust mite allergen extract
- hyaluronidase
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyzine
- hyoscyamine
I
- ifosfamide
- iloperidone
- imatinib
- imipramine
- incobotulinumtoxinA
- indapamide
- infliximab
- ipratropium
- ipratropium nasal
- isocarboxazid
- isoflurophate ophthalmic
- isoniazid
K
L
- labetalol
- lamotrigine
- lasmiditan
- lemborexant
- lenacapavir
- letibotulinumtoxinA
- levetiracetam
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- linezolid
- lisdexamfetamine
- lithium
- lofexidine
- lonapegsomatropin
- loperamide
- lorazepam
- lorcaserin
- loxapine
- lumateperone
- lurasidone
M
- maprotiline
- mavorixafor
- mazindol
- meclizine
- melatonin
- memantine
- mepenzolate
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methsuximide
- methyclothiazide
- methyldopa
- methylene blue
- metoclopramide
- metolazone
- metoprolol
- metyrosine
- mibefradil
- midazolam
- milnacipran
- mirabegron
- mirtazapine
- mitotane
- mixed grass pollens allergen extract
- molindone
- morphine
- morphine liposomal
N
- nabilone
- nadolol
- nalbuphine
- naratriptan
- nebivolol
- nefazodone
- nemolizumab
- neostigmine
- nilotinib
- nitrofurantoin
- nitroglycerin
- nortriptyline
O
- olanzapine
- oliceridine
- olopatadine nasal
- olutasidenib
- omaveloxolone
- onabotulinumtoxinA
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- oxamniquine
- oxazepam
- oxcarbazepine
- oxybutynin
- oxycodone
- oxymorphone
- ozanimod
P
- paliperidone
- palonosetron
- panobinostat
- paraldehyde
- paramethadione
- paroxetine
- peanut allergen powder
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phentermine
- phenylephrine
- phenylephrine ophthalmic
- phenytoin
- physostigmine
- physostigmine ophthalmic
- pilocarpine
- pilocarpine ophthalmic
- pimozide
- pindolol
- pirtobrutinib
- pitolisant
- polythiazide
- potassium chloride
- potassium citrate
- prabotulinumtoxinA
- pralsetinib
- pramipexole
- pramlintide
- pregabalin
- pretomanid
- primidone
- procainamide
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propantheline
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- prucalopride
- pyridostigmine
- pyrilamine
Q
R
- ragweed pollen allergen extract
- ramelteon
- ranolazine
- rasagiline
- remifentanil
- remimazolam
- revefenacin
- rilonacept
- rimabotulinumtoxinB
- risperidone
- ritonavir
- rivastigmine
- rizatriptan
- rolapitant
- ropeginterferon alfa-2b
- ropinirole
- rotigotine
- rufinamide
S
- safinamide
- sarilumab
- satralizumab
- scopolamine
- secobarbital
- secretin
- secukinumab
- selegiline
- sertraline
- sibutramine
- siltuximab
- sodium iodide i-123
- sodium iodide-i-131
- sodium oxybate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotalol
- st. john's wort
- stiripentol
- sufentanil
- sumatriptan
- suvorexant
T
- tacrine
- tapentadol
- tarlatamab
- tasimelteon
- tebentafusp
- teclistamab
- tedizolid
- temazepam
- terbinafine
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- ticlopidine
- timolol
- timolol ophthalmic
- timothy grass pollen allergen extract
- tiotropium
- tirzepatide
- tizanidine
- tocilizumab
- tolcapone
- tolterodine
- topiramate
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trichlormethiazide
- trichophyton skin test
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troglitazone
- trospium
- tryptophan
U
V
- valbenazine
- valdecoxib
- valerian
- valproic acid
- vemurafenib
- venlafaxine
- vigabatrin
- vilazodone
- viloxazine
- vimseltinib
- vortioxetine
Z
Extendryl DM alcohol/food interactions
There are 3 alcohol/food interactions with Extendryl DM (chlorpheniramine / dextromethorphan / methscopolamine).
Extendryl DM disease interactions
There are 21 disease interactions with Extendryl DM (chlorpheniramine / dextromethorphan / methscopolamine) which include:
- autonomic neuropathy
- GI obstruction
- glaucoma
- obstructive uropathy
- reactive airway diseases
- myasthenia gravis
- infectious diarrhea
- cardiac disease
- tachycardia
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- coronary artery disease
- gastric ulcer
- gastroesophageal reflux
- ulcerative colitis
- hypertension
- hyperthyroidism
- diarrhea
- fever
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More about Extendryl DM (chlorpheniramine / dextromethorphan / methscopolamine)
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.