DynaCirc CR Side Effects

Generic name: isradipine

Medically reviewed by Drugs.com. Last updated on Dec 14, 2024.

Note: This document provides detailed information about DynaCirc CR.

Applies to isradipine: oral capsule Side Effects associated with isradipine. Some dosage forms listed on this page may not apply specifically to the brand name DynaCirc CR.

Applies to isradipine: oral capsule.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

Low blood pressure (hypotension) may occur while taking this medicine. Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness .

This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of face, arms, hands, lower legs, or feet; tingling of hands or feet; or unusual weight gain or loss .

Serious side effects of DynaCirc CR

Along with its needed effects, isradipine (the active ingredient contained in DynaCirc CR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking isradipine:

Get emergency help immediately if any of the following symptoms of overdose occur while taking isradipine:

Symptoms of Overdose

• blurred vision
• confusion
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• flushing
• sweating

Other side effects of DynaCirc CR

Some side effects of isradipine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to isradipine: oral capsule, oral tablet extended release.

General adverse events

Isradipine (the active ingredient contained in DynaCirc CR) is generally well-tolerated. Most side effects occurred as commonly as with placebo in placebo-controlled trials, except for flushing, headache, and palpitations.^[Ref]

Cardiovascular

Cardiovascular side effects are among the most common, and are related to the vasodilatory properties of isradipine (the active ingredient contained in DynaCirc CR) Peripheral edema and flushing are reported in 3% to 14% of patients, being more common at higher doses. Dizziness occurs in 3% to 8% of patients.^[Ref]

Palpitations or a greater awareness of heart beats is reported in 1% to 5% of patients. Flushing and palpitations are more likely with dosages greater than 5 mg daily; women have reported flushing more than men. Edema was reported in up to 22% of patients in one study (mean dose was 5.9 mg TID). In large studies, the incidence of edema is less than 3%, and appeared to be more likely in patients greater than 60 years of age.

Isradipine does not appear to adversely affect plasma lipids.^[Ref]

Nervous system

Nervous system side effects are probably related to the vasodilatory effects of isradipine (the active ingredient contained in DynaCirc CR) Headache is reported in 9% to 30% of patients and fatigue is reported in 7% of patients.^[Ref]

Headache was reported in up to 16% of patients in one study, although the mean dose was 5.9 mg three times daily to treat angina pectoris. Headache is more likely with dosages greater than 5 mg daily. Visual disturbances are reported in less than 2% of patients. Sleep disturbances are reported in 0.1% of patients.^[Ref]

Gastrointestinal

Gastrointestinal side effects are unusual, and include constipation in less than 2% of patients.^[Ref]

Anorexia, nausea, vomiting, and diarrhea are reported in less than 4% of patients.^[Ref]

Respiratory

Respiratory system complaints include dyspnea and cough in 2% of patients.^[Ref]

Musculoskeletal

Musculoskeletal pain is reported in 1% of patients.^[Ref]

Dermatologic

Dermatologic complaints of "disturbed skin sensation" are reported in less than 4% of patients.^[Ref]

Hypersensitivity

Hypersensitivity reactions to isradipine (the active ingredient contained in DynaCirc CR) are rare. Pruritus, urticaria, and angioedema have been reported.^[Ref]

See also:

Further information

DynaCirc CR side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer