Durysta Side Effects

Generic name: bimatoprost ophthalmic

Medically reviewed by Drugs.com. Last updated on May 9, 2024.

Note: This document provides detailed information about Durysta Side Effects associated with bimatoprost ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Durysta.

Applies to bimatoprost ophthalmic: implant, solution.

Precautions

Your eye doctor will want to examine your eyes at regular visits to make sure that the medicine is working properly and is not causing unwanted effects.

If itching, redness, swelling, or other signs of eye or eyelid irritation occur, check with your doctor. These signs may mean that you are allergic to bimatoprost.

Check with your doctor if you have an injury, trauma, or infection in your eye or if you are scheduled to have an eye surgery. Your doctor may want you to use a fresh bottle of bimatoprost in case the present bottle has become contaminated during use.

If you are using this medication for eyelash growth, be careful to apply as directed and wipe off any excess that comes into contact with other skin areas. There is a potential for hair growth in other areas this medicine comes into contact with.

While you are using bimatoprost, the iris (colored part) of your treated eye(s) may slowly become more brown in color. The change in color of the iris is noticeable usually within several months or years from the start of treatment with bimatoprost. In addition, there may be a darkening of the eyelid skin color. Also, your eyelashes may become longer, thicker, and darker. These changes to the iris, eyelid, and lashes may be permanent even if you stop using bimatoprost. Also, these changes to the iris, eyelid, and lashes will affect only the eye being treated with bimatoprost. Therefore, if only one eye is being treated, only that eye may develop darker iris, eyelid, and eyelashes and other changes to the eyelashes, and you may have differently appearing eyes. Check with your doctor if you have any questions about this.

Common side effects of Durysta

Some side effects of bimatoprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Durysta

Along with its needed effects, bimatoprost ophthalmic (the active ingredient contained in Durysta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking bimatoprost ophthalmic:

For healthcare professionals

Applies to bimatoprost ophthalmic: intraocular implant, ophthalmic solution.

General adverse events

The most frequently reported adverse reactions were eyelash growth, conjunctival hyperemia, and ocular pruritus.^[Ref]

Ocular

• Very common (10% or more): Growth of eyelashes (up to 45%), conjunctival hyperemia (up to 44%), ocular pruritus (up to 15%)
• Common (1% to 10%): Allergic conjunctivitis, asthenopia, blepharitis, blurred vision, cataract, conjunctival edema, conjunctival hemorrhage, corneal erosion, dry eye, eye discharge, eye irritation, eye pain, eye pruritus, eyelash darkening, eyelid pruritus, foreign body sensation, increased iris pigmentation, lacrimation increased, ocular burning, ocular dryness, ocular irritation, photophobia, punctate keratitis, superficial punctate keratitis, tearing, visual disturbance, worsening of visual acuity
• Uncommon (0.1% to 1%): Blepharospasm, eyelid edema, eyelid margin crusting, eyelid retraction, iris hyperpigmentation, iritis, retinal hemorrhage, uveitis
• Rare (0.01% to 0.1%): Corneal calcification
• Frequency not reported: Blepharal pigmentation, cystoid macular edema, eye edema, eyelash changes, eyelid sulcus deepening, intraocular inflammation, macular edema, signs/symptoms of eye allergy
• Postmarketing reports: Enophthalmos^[Ref]

Corneal calcification occurred in patients with significant corneal damage using formulations containing phosphate.^[Ref]

Dermatologic

• Common (1% to 10%): Eyelid erythema, hirsutism, hypertrichosis, periocular skin hyperpigmentation, periorbital erythema, pigmentation of periocular skin, skin hyperpigmentation
• Uncommon (0.1% to 1%): Abnormal hair growth, dry skin, madarosis, pruritus
• Frequency not reported: Lid changes, periorbital changes, pigmentation, signs/symptoms of allergic dermatitis^[Ref]

Immunologic

• Common (1% to 10%): Colds, infections^[Ref]

Respiratory

• Common (1% to 10%): Upper respiratory tract infections
• Frequency not reported: Asthma, asthma exacerbation, chronic obstructive pulmonary disease (COPD) exacerbation, dyspnea
• Postmarketing reports: Asthma-like symptoms^[Ref]

Nervous system

• Common (1% to 10%): Headache
• Uncommon (0.1% to 1%): Dizziness, vertigo^[Ref]

Local

• Common (1% to 10%): Instillation site irritation^[Ref]

Hepatic

• Common (1% to 10%): Abnormal liver function tests^[Ref]

Other

• Uncommon (0.1% to 1%): Asthenia^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension^[Ref]

Gastrointestinal

• Uncommon (0.1% to 1%): Nausea^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Depression^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity, hypersensitivity reaction^[Ref]

See also:

Further information

Durysta side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer