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Durysta Side Effects

Generic name: bimatoprost ophthalmic

Medically reviewed by Last updated on Feb 6, 2024.

Note: This document contains side effect information about bimatoprost ophthalmic. Some dosage forms listed on this page may not apply to the brand name Durysta.

Applies to bimatoprost ophthalmic: implant, solution.

Serious side effects of Durysta

Along with its needed effects, bimatoprost ophthalmic (the active ingredient contained in Durysta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking bimatoprost ophthalmic:

Less common

Other side effects of Durysta

Some side effects of bimatoprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to bimatoprost ophthalmic: intraocular implant, ophthalmic solution.


The most frequently reported adverse reactions were eyelash growth, conjunctival hyperemia, and ocular pruritus.[Ref]


Very common (10% or more): Growth of eyelashes (up to 45%), conjunctival hyperemia (up to 44%), ocular pruritus (up to 15%)

Common (1% to 10%): Allergic conjunctivitis, asthenopia, blepharitis, blurred vision, cataract, conjunctival edema, conjunctival hemorrhage, corneal erosion, dry eye, eye discharge, eye irritation, eye pain, eye pruritus, eyelash darkening, eyelid pruritus, foreign body sensation, increased iris pigmentation, lacrimation increased, ocular burning, ocular dryness, ocular irritation, photophobia, punctate keratitis, superficial punctate keratitis, tearing, visual disturbance, worsening of visual acuity

Uncommon (0.1% to 1%): Blepharospasm, eyelid edema, eyelid margin crusting, eyelid retraction, iris hyperpigmentation, iritis, retinal hemorrhage, uveitis

Rare (0.01% to 0.1%): Corneal calcification

Frequency not reported: Blepharal pigmentation, cystoid macular edema, eye edema, eyelash changes, eyelid sulcus deepening, intraocular inflammation, macular edema, signs/symptoms of eye allergy

Postmarketing reports: Enophthalmos[Ref]

Corneal calcification occurred in patients with significant corneal damage using formulations containing phosphate.[Ref]


Common (1% to 10%): Eyelid erythema, hirsutism, hypertrichosis, periocular skin hyperpigmentation, periorbital erythema, pigmentation of periocular skin, skin hyperpigmentation

Uncommon (0.1% to 1%): Abnormal hair growth, dry skin, madarosis, pruritus

Frequency not reported: Lid changes, periorbital changes, pigmentation, signs/symptoms of allergic dermatitis[Ref]


Common (1% to 10%): Colds, infections[Ref]


Common (1% to 10%): Upper respiratory tract infections

Frequency not reported: Asthma, asthma exacerbation, chronic obstructive pulmonary disease (COPD) exacerbation, dyspnea

Postmarketing reports: Asthma-like symptoms[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness, vertigo[Ref]


Common (1% to 10%): Instillation site irritation[Ref]


Common (1% to 10%): Abnormal liver function tests[Ref]


Uncommon (0.1% to 1%): Asthenia[Ref]


Common (1% to 10%): Hypertension[Ref]


Uncommon (0.1% to 1%): Nausea[Ref]


Uncommon (0.1% to 1%): Depression[Ref]


Frequency not reported: Hypersensitivity, hypersensitivity reaction[Ref]


1. (2001) "Product Information. Lumigan (bimatoprost ophthalmic)." Allergan Inc

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.