Disalcid Side Effects
Generic name: salsalate
Medically reviewed by Drugs.com. Last updated on Nov 19, 2024.
Note: This document provides detailed information about Disalcid Side Effects associated with salsalate. Some dosage forms listed on this page may not apply specifically to the brand name Disalcid.
Applies to salsalate: oral tablets.
Important warnings
This medicine can cause some serious health issues
-
Cardiovascular Risk
- Possible increased risk of serious (sometimes fatal) cardiovascular thrombotic events (e.g., MI, stroke).b Risk may increase with duration of use.b Individuals with cardiovascular disease or risk factors for cardiovascular disease may be at increased risk.b (See Cardiovascular Effects under Cautions.)
- Contraindicated for the treatment of pain in the setting of CABG surgery.b
-
GI Risk
- Increased risk of serious (sometimes fatal) GI events (e.g., bleeding, ulceration, perforation of the stomach or intestine).b Serious GI events can occur at any time and may not be preceded by warning signs and symptoms.b Geriatric individuals are at greater risk for serious GI events.b (See GI Effects under Cautions.)
Side effects include:
Tinnitus, nausea, hearing impairment, rash, vertigo.
For healthcare professionals
Applies to salsalate: oral capsule, oral tablet.
General adverse events
The most frequently reported side effects were usually reversible and included tinnitus, nausea, hearing impairment, rash, and vertigo.[Ref]
Gastrointestinal
Cardiovascular
- Frequency not reported: Hypotension[Ref]
Dermatologic
- Frequency not reported: Rash, angioedema, urticaria[Ref]
Hepatic
- Frequency not reported: Hepatic function abnormal, hepatitis[Ref]
Renal
- Frequency not reported: Nephritis[Ref]
Respiratory
- Frequency not reported: Bronchospasm[Ref]
Other
- Frequency not reported: Tinnitus, hearing impaired, vertigo, creatinine clearance decreased[Ref]
Immunologic
- Frequency not reported: Anaphylactic shock[Ref]
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References
1. (2017) "Product Information. Salsalate (salsalate)." Amneal Pharmaceuticals
2. (2001) "Product Information. Disalcid (salsalate)." 3M Pharmaceuticals
3. Phillips BB, Joss JD, Mulhausen PL (2002) "Blood pressure elevation in a patient treated with salsalate." Ann Pharmacother, 36, p. 624-7
More about Disalcid (salsalate)
- Check interactions
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- Drug images
- Dosage information
- During pregnancy
- Drug class: salicylates
- Breastfeeding
Patient resources
Professional resources
Related treatment guides
Further information
Disalcid side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.