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Diltia XT Side Effects

Generic name: diltiazem

Medically reviewed by Drugs.com. Last updated on Mar 11, 2024.

Note: This document provides detailed information about Diltia XT Side Effects associated with diltiazem. Some dosage forms listed on this page may not apply specifically to the brand name Diltia XT.

Applies to diltiazem: oral capsule extended release, oral capsule extended release 12 hr, oral capsule extended release 24 hr, oral tablet, oral tablet extended release, oral tablet extended release 24 hr.

Other dosage forms:

Serious side effects of Diltia XT

Along with its needed effects, diltiazem (the active ingredient contained in Diltia XT) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking diltiazem:

More common

  • body aches or pain
  • congestion
  • cough
  • dryness or soreness of the throat
  • fever
  • hoarseness
  • runny nose
  • tender or swollen glands in the neck
  • trouble swallowing
  • voice changes

Less common

  • chest pain, discomfort, or tightness
  • chills
  • diarrhea
  • difficult or labored breathing
  • feeling faint, dizzy, or lightheaded
  • feeling of warmth or heat
  • flushing or redness of the skin, especially on the face and neck
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • loss of appetite
  • muscle aches and pains
  • nausea
  • shivering
  • slow or irregular heartbeat
  • sweating
  • swelling of the hands, ankles, feet, or lower legs
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting

Incidence not known

  • blistering, peeling, or loosening of the skin
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • no heartbeat
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • sores, ulcers, or white spots in the mouth or on the lips

Other side effects of Diltia XT

Some side effects of diltiazem may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • sneezing
  • stuffy nose

Less common

  • acid or sour stomach
  • belching
  • constipation
  • continuing ringing or buzzing or other unexplained noise in the ears
  • degenerative disease of the joint
  • difficulty with moving
  • hearing loss
  • heartburn
  • indigestion
  • lack or loss of strength
  • muscle aching or cramping
  • muscle pains or stiffness
  • pain or tenderness around the eyes and cheekbones
  • rash
  • stomach discomfort, upset, or pain
  • swollen joints

Incidence not known

  • loss or thinning of the hair

For healthcare professionals

Applies to diltiazem: compounding powder, intravenous powder for injection, intravenous solution, oral capsule extended release, oral tablet, oral tablet extended release.

General

The most commonly reported side effects include edema, headache, and dizziness.[Ref]

Cardiovascular

A patient with Prinzmetal's angina developed asystole after a single, 60 mg dose.

Myocardial infarction was not readily distinguishable from the natural history of the disease.

Vasodilatory events (e.g., peripheral edema, headache, flushing) are dose-related and may be more common in elderly patients.

First degree AV block and sinus bradycardia occurred more frequently with higher doses.[Ref]

Other

Gastrointestinal

Dermatologic

Well-documented cases of rashes (as leukocytoclastic vasculitis) have been reported, but a definitive between these events and this drug have not been established.

Lichenoid keratosis and hyperpigmentation occurred in skin exposed to the sun.[Ref]

Respiratory

Nervous system

Dizziness occurred more frequently with higher doses.[Ref]

Musculoskeletal

Metabolic

Genitourinary

Ocular

Local

Psychiatric

Hepatic

There were rare cases of clinical hepatitis that were reversible with discontinuation of this drug.[Ref]

Hematologic

Hypersensitivity

Endocrine

References

1. (2002) "Product Information. Cardizem (diltiazem)." Hoechst Marion Roussel

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

4. (2011) "Product Information. Dilacor XR (diltiazem)." Aventis Pharmaceuticals

Further information

Diltia XT side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.