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Diclofenac / fluorouracil topical Side Effects

Applies to diclofenac / fluorouracil topical: topical cream

General

The most commonly reported side effects were burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, and ulceration.[Ref]

Cardiovascular

Frequency not reported: Ventricular septal birth defects[Ref]

Hematologic

Frequency not reported: Eosinophilia, thrombocytopenia, toxic granulation, leukocytosis[Ref]

Dermatologic

Frequency not reported: Alopecia, blistering, bullous pemphigoid, scaling, suppuration, swelling, telangiectasia, tenderness, urticaria, skin rash[Ref]

Immunologic

Frequency not reported: Herpes simplex[Ref]

Local

Frequency not reported: Discomfort, ichthyosis[Ref]

Ocular

Frequency not reported: Conjunctival reaction, corneal reaction, lacrimation

Psychiatric

Frequency not reported: Emotional upset, insomnia, irritability[Ref]

Gastrointestinal

Frequency not reported: Medicinal taste, stomatitis, cleft lip and palate birth defects[Ref]

Respiratory

Frequency not reported: Nasal irritation[Ref]

Metabolic

Frequency not reported: Fluid retention, edema[Ref]

Other

Frequency not reported: Miscarriage

References

1. "Product Information. Fluorac (diclofenac-fluorouracil topical)." Burke Therapeutics, Hot Springs, AR.

Not all side effects for diclofenac / fluorouracil topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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