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Diclofenac / fluorouracil topical Side Effects

Applies to diclofenac/fluorouracil topical: topical cream


The most commonly reported side effects were burning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, and ulceration.[Ref]


Frequency not reported: Ventricular septal birth defects[Ref]


Frequency not reported: Eosinophilia, thrombocytopenia, toxic granulation, leukocytosis[Ref]


Frequency not reported: Alopecia, blistering, bullous pemphigoid, scaling, suppuration, swelling, telangiectasia, tenderness, urticaria, skin rash[Ref]


Frequency not reported: Herpes simplex[Ref]


Frequency not reported: Discomfort, ichthyosis[Ref]


Frequency not reported: Conjunctival reaction, corneal reaction, lacrimation


Frequency not reported: Emotional upset, insomnia, irritability[Ref]


Frequency not reported: Medicinal taste, stomatitis, cleft lip and palate birth defects[Ref]


Frequency not reported: Nasal irritation[Ref]


Frequency not reported: Fluid retention, edema[Ref]


Frequency not reported: Miscarriage


1. "Product Information. Fluorac (diclofenac-fluorouracil topical)." Burke Therapeutics, Hot Springs, AR.

Some side effects of diclofenac / fluorouracil topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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