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User Reviews for Imiquimod topical

Also known as: Aldara, Zyclara

Imiquimod topical has an average rating of 6.9 out of 10 from a total of 415 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 21% reported a negative effect.

Condition Avg. Rating Reviews Compare
Human Papilloma Virus  
6.9
265 reviews 6 medications
Basal Cell Carcinoma  
6.9
74 reviews 7 medications
Keratosis  
7.1
59 reviews 17 medications
Condylomata Acuminata  
6.8
14 reviews 6 medications
Molluscum Contagiosum  Off-label
1.0
3 reviews 1 medications
Summary of Imiquimod topical reviews 6.9 415 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Imiquimod topical

Anonymous · Taken for 1 to 6 months August 10, 2019

Aldara (imiquimod) for Human Papilloma Virus: “I contracted HPV through someone...I don't know who but I have been having my fair share of fun. I was nervous at first but the people who I continued to see didn't care. I initially had them burned off on the shaft of my penis but it left a scar. So when they came back, I decided to go the cream route. Luckily places (like the LGBT center) provide cheap prescriptions for people who can't afford them like me (paid like $10-15 for a good supply). Anyways, I've been using Aldara for 4-5 weeks now and it's finally working it's magic. I've had it twice where it seems to open up as a sore and then scab up and heal. People definitely sweat this as the end of their sex lives or stress over it too much. It's not the end of the world..it will heal..and our bodies will go back to "normal". Hang in there!!!”

9 / 10
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Anonymous August 6, 2020

Aldara (imiquimod) for Human Papilloma Virus: “I am happy to report that I did not experience any side effect symptoms at all except maybe some very mild sensitivity where the medicine was placed. My routine included taking a shower before bed, waiting 10 minutes to completely dry, apply a little bit of vaseline on the surrounding skin that was not affected, and rubbing a tiny amount onto the warts. In the morning, I make sure to rinse off the medication as soon as I wake up and take my daily vitamins to boost my immune systems even further. At first I was nervous nothing was happening because I didn’t feel any symptoms. After the second dose, I noticed the warts shrinking dramatically. After the third, all the small ones have disappeared and the one medium one is almost gone. Make sure you only use a small amount. My doctor said to throw away anything unused and start a new satchel every time. Anyways, I’m here to say that this medication really works and there is definitely a light at the end of the tunnel!!”

10 / 10
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Bobbie · Taken for 1 to 6 months March 1, 2020

Aldara (imiquimod) for Basal Cell Carcinoma: “Just finished week 6 of aldara for BCC.....now waiting for the scabs and redness to go away. 6 weeks was a long treatment, but well worth it instead of MOHS surgery. You MUST wash hands before and after applying and you MUST wash the application area(s) after 8 hours. I applied the cream on the tip of my nose but the entire nose reacted! I applied the cream Monday to Friday and took Saturday and Sunday off. Weeks 3 and 4 were the worst....lots of oozing and dark scabs. You can use makeup....start with a color corrector, then a concealer and/or foundation. I’m now waiting for the scabs and redness to go away. There are no instructions on what to do after the 6 weeks, so I’m still washing the area and putting moisturizer on it twice a day.”

10 / 10
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Dee K · Taken for less than 1 month November 12, 2015

For Human Papilloma Virus: “I am female and was diagnosed with genital warts when I was 22 years old and I thought my life was over. I was prescribed Aldara cream and my gyno told me to use just a tiny bit and to try to ONLY put it on the warts and not the surrounding skin. I remember feeling a little soreness but nothing that I couldn't handle. I had a mild case of warts near the opening of my vagina and they flattened after a week and were completely cleared after 2.5 weeks... I couldn't believe it! Want to know the best part? I am 33 years old and they have never come back! Turns out my life wasn't over after all!”

10 / 10
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Itwillgo April 7, 2020

Aldara (imiquimod) for Human Papilloma Virus: “I used Aldara for around 10 weeks. I had anal warts at the time and one on my Gooch. Aldara made my ass really red and raw and warts didn't seem to go away or change in appearance. What I did notice though was that warts went away over the next 3 months without using anything as I was travelling and didn't have any supply. Aldara is used to help boost the immune system in targeting the HPV virus (Which by the way is NOT permanent) there is so much old information out there and those of you who are just beginning your journey know that it is temporary (I know it sucks and there are so many emotions BUT you will come out the other side!). My dermatologist told me this first hand and people who are healthy will naturally clear this virus. It incubated for around 6 months and then symptoms appear. Those with Immune deficiencies will struggle to clear it, unfortunately. Cryotherapy takes the wart off and Aldara boosts the immune system to fight infection.”

6 / 10
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M56 August 26, 2018

Aldara (imiquimod) for Human Papilloma Virus: “Aldara is super efficient. Here is my advice: -only apply 3 times a week, reduce if you feel too much pain. -when starting the treatment, only apply a really tiny amount of cream on each wart with the end of a cotton bud. Only when you are ready, start applying a tiny bit more but it should stay minimal. -it will create discomfort. Use baby wipes for the toilet; buy an intimate gel to take care of the area that is infected. I took 2 showers a day during the treatment to keep the area clean at all times. No pyjama bottoms to avoid any contact. -the pain is OKAY. It can burn healthy skin in the night when the warts with cream rub against it. Put some tiny plasters opposite the wart for the night. It gets itchy during the day, but stay busy. - be positive: eat healthily, stop smoking. Have someone to help you go through it. Had 6 genital warts and 5 were completely gone by week 2. Still treating 1 but it's now barely visible. Go for it and good luck, stay positive!”

10 / 10
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Anonymous December 12, 2019

Aldara (imiquimod) for Basal Cell Carcinoma: “This is my 5th go-around with Aldara. I've previously treated 3 facial BCCs and 2 pre-cancerous areas. I insist on a biopsy the minute I have even a tiny, non-healing lesion and I have never been wrong. I notice nothing for about 14 days, then all the big reaction breaks loose! Painful, weeping, 2-cm sores requiring gauze just to sleep. I look like a leper. This latest treatment came with massive headaches, joint aches, abdominal pain and flu-like malaise which began during week three and continues unabated. That said, I have never had a lesion recur; there is no scarring whatsoever; and the healing after stopping the applications is swift-- all sores gone within about two weeks. It can take two to four months before the skin thickens completely back to normal, and I am compulsive about sun-screening-- especially any pre-treated areas. The treatment isn't fun, and at $400 a pop it's a bit excessive. But the results for me have been consistently great.”

10 / 10
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Frequently asked questions

Samantha May 22, 2020

Aldara (imiquimod) for Basal Cell Carcinoma: “After being perfectly healthy my entire life, used Aldara cream for 10 days on BC on chest. I thought it would be least invasive. After developing large "croissant" size growth of black on my chest, worsening fatigue, migraine, severe diarrhea, low grade fevers, red rash over arms and legs, large tennis ball size red swollen growth on shoulder, and dizziness was admitted to hospital. At this point, I was told later, near death. I spent 3 days in isolation, seen by infectious disease specialist, internal medicine, gastroenterologist. Dx: recurrent C-dif bowel infection-Colitis, MRSA infection, severe anemia. Received 2 blood transfusions, iron, upper scope of GI tract, MRI of brain, chest xray, multiple blood workups. Anemic blood level of 7 (normal blood level is 14). Weight loss at 20 pounds. This drug was SYSTEMIC in my body, and nearly ended my life. Do NOT take the medication. My new dermatologist stated he will never prescribe it again after my experience.”

1 / 10
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liv7744 October 26, 2020

Aldara (imiquimod) for Human Papilloma Virus: “I got prescribed Aldara by my local sexual health clinic to treat genital warts. I thought my warts were the end of the world until I used Aldara. After applying the cream twice (as directed, only on the warts and every other night, washing it off in the morning) boy did I regret my life choices. My entire vagina swelled up the following day, and ulcer-type sores appeared EVERYWHERE in that area. I couldn’t move without being in excruciating pain and I almost passed out every time I peed. I ended up in hospital on a 7 day course of antibiotics, as well as dihydrocodiene to manage the pain. STAY AWAY FROM THIS CREAM - it should not be prescribed!!! After doing extensive reading online about Aldara, I quickly realised that so many people had been through the same as me. The warts eventually go away on their own, or there are other treatments such as freezing them off. Please please stay away from this cream.”

1 / 10
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... March 21, 2019

Aldara (imiquimod) for Human Papilloma Virus: “I’ve been on the aldara for a week. My first application was okay no pain whatsoever. Note: I use small amounts overnight every alternative day on infected area on my labia. I realized that I was getting really tired the day after but that was it. After the first application it just got worse, the pain is unbearable. I can’t sleep at night because of the pain . I now have pink sores around the uninfected parts . The space between my thighs and vagina are pink and saw it also looks like eczema. But with all this pain, the cream is working wonders , in just a week 70% of my warts are gone. Just the stubborn ones are left. They are big but are getting smaller, but is it worth the pain ? I think so because I’m still continuing with it . I’m desperate for these to be gone and the cream is sure removing them . If you can’t take pain then don’t but if you’re a hardcore go getter like me, it’s worth the try . I hope this information helps someone this is my honest experience.”

8 / 10
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Ads · Taken for 1 to 6 months December 24, 2019

Aldara (imiquimod) for Human Papilloma Virus: “First off you're in for a pretty bad 16 weeks or longer! There's no sugar coating it. Less cream is more and more is too much, you'll notice the warts will get worse before they get better that's your body trying to fight it off. Avoid sex at all cost I say that because I couldn't resist 3 times during the treatment and I went through a lot of pain with ulcers due to the friction however sometimes you can get away with light masturbation. If you get ulcers I used lignocaine gel 2% it's a anaesthesia that just drips on. Try and clean the area twice a day and if you have ulcers just run cool-warm water over it no matter how painful it is to keep it clean so you don't get infection. If you get really bad ulcers it's ok to stop treatment for a week to heal then continue treatment I had to stop treatment 3 times due to bad ulcers. The final thing to say is don't give up it took 13 long weeks till I finally saw improvement and I'm about to hit 16 weeks and the warts are pretty almost gone.”

6 / 10
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Wartson · Taken for less than 1 month May 13, 2020

Aldara (imiquimod) for Human Papilloma Virus: “I was skeptical i even booked an appointment to get my foreskin circumcised. My warts were all around my inner foreskin so when i pulled down my foreskin they were all around that area of my penis. Dr refered to them as circumferential. They were not subtle at all as well so many i lost count. Well i got aldara. Its expensive. I got 9 sachets used 1 sachet for 2 applications (closed an open sachet with a peg). I'd apply it every 2nd day. When applying, i applied it on the warts then i'd rub into them till it disappeared. After that id apply again and left it on the warts till it dissolved by itself. I applied it from 27th of April to the 12th of May. And they started shrinking and before I knew it they were all gone. For me there was ZERO pain in the whole process. I recommend it highly. Trust me it works. And works well”

9 / 10
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myaka April 15, 2011

Aldara (imiquimod) for Basal Cell Carcinoma: “When treating for Basal Cell Carcinoma, in my case the arm, HEED THE WARNING to not use on sore or broken skin, which should include recently biopsied lesions to avoid any confusion. Wait until the excision site has healed. I did not receive this instruction and began using it that night. The pain was beyond description, reached deep into the muscle tissue, and lasted for hours. Follow-up phone calls of course confirmed the oversight. ”

5 / 10
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LAD · Taken for 1 to 6 months December 12, 2018

For Basal Cell Carcinoma: “I’ve used this multiple times. All on the face. While the treatment is not pretty or painless the results are wonderful. With surgery I would have had to undergo plastic surgery to rebuild cheek area. This treatment was well worth the pain and discomfort. Skin is healthy and no surgeries. Be prepared to be stared at and don’t plan any important business/social event during treatment. It truly is ugly. But again, 6 weeks of discomfort for exceptional result is worth it to me. My skin was covered in large oozing scabs that didn’t feel good. Washing was miserable. But you can get through anything for 6 weeks for such great results. I’d do it again in a heartbeat. Pain, discomfort, headache, better than surgery any day.”

10 / 10
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Bob Moon February 19, 2013

Aldara (imiquimod) for Basal Cell Carcinoma: “Used it for 3 weeks. 5 days on, 2 off, and so on. 1st week comes out like pimples, second they break, third they dry. Hurts, sure but not impossible. Works perfectly. Fever, drowsiness, headaches, but its worth it. I have used it for the last 5 years once a year for face skin problems.”

10 / 10
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Scott876123 December 31, 2013

Zyclara (imiquimod) for Keratosis: “Have finished my first two week application and am about to start the second. I'm a 44 yo fair skinned male who rarely wore sunscreen as a kid and had my share of sunburns. Had a few Actinic Keratosis spots that kept coming back so doc put me on Zyclara for my forehead and cheeks. After reading the horror stories I was absolutely dreading it. To my delight the side effects were not bad at all, and I just had 4-5 spots flare up that looked like acne. I never post to things like this, but I hope some see this and know that not all people have the horrible effects of it. I can certainly sympathize with the ones who do though.”

8 / 10
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Tammy · Taken for less than 1 month March 8, 2021

Aldara (imiquimod) for Human Papilloma Virus: “This drug is magicccccc!! Now read this carefully. Do NOT apply too much! You don’t have to finish the whole sachet. I got two warts on my genital area on extremely sensitive skin. They weren’t really bothering me but I was worried about them spreading to other places. I took a q-tip and applied a very thin layer on each making sure to rub until the cream disappeared. I tried to leave it on a bit to dry completely so the discharge won’t spread it to other places of the vagina. GET RID OF THE SACHET ONCE YOU OPEN IT, don’t reuse it. My wart fell off in one day honestly I couldn’t even believe it. The cream really worked for me, hope it works for you with no crazy side effects.”

10 / 10
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Not a paid review - D November 25, 2019

For Human Papilloma Virus: “I NEVER leave reviews for anything... but this one hits a nerve. I contracted anal warts - no bloody idea how to be honest, but anyways. 7 sessions of cryo didn't help because it was too big by then. It measures about 1.5x2.5cm cluster, it was becoming painful to sit. I was shattered. Dr suggested Aldara, but even she said she wasn't confident because it is quite big. First two weeks it was very itchy, very sore didn't see much difference. Then out of no where I see parts of the wart simply falling off.. it has now reduced to about 30% of the size in 3.5 weeks. Im using it every 2 days. Keen to see what another few weeks will do. If you are in pain during this period, take pain relievers. If it is itchy, use creams or powders to assist. There other things out there to help you with the temporary side effects. The end results will reward you! I hope this information has helped another person somewhere out there.. ! Good luck! In bad times, there will eventually be good times!”

9 / 10
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Kel · Taken for less than 1 month October 2, 2019

Aldara (imiquimod) for Basal Cell Carcinoma: “For 18 months I had a sore on my nose that would bleed scab than disappear, finally I had it checked (I should have known better, have family history of skin cancer) came back as a BCC. I'm now 5 weeks into my use of Aldara. for the first 3 weeks didn't really have any signs of it doing to much well now at week 5, my nose is hard scab like and a lot bigger area than I had thought. I wouldn't say its sore just uncomfortable and itchy at times. I guess once completed and healed time will tell if it completely worked, my doctor gives it an 80% chance and if not, its surgery for me. I hope this isn't all for nothing but feel it has been worth the chance and do feel that it has done its job well, so far so good. I'm in AUS and cost was $50.”

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Freeeee April 5, 2011

Aldara (imiquimod) for Human Papilloma Virus: “I was extremely hesitant to use this medicine because of the price and because I had read horror stories about it online. But I was desperate because of unsightly warts, so I took the plunge. I made sure to apply with a magnification mirror and a q-tip. I can't stress enough how important it was to ONLY apply it exactly where the warts were. My side effects included swelling and itching around the affected area and some fatigue/aches. After using it 4 times, my warts were gone. Worth it worth it worth it. Just be careful not to put it on any healthy skin.”

10 / 10
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Dana Lee · Taken for 1 to 6 months May 28, 2017

For Basal Cell Carcinoma: “I am not going to sugar coat this for you, It is a painfully itchy, sleepless, process. Not for the faint at heart. Put on your big girl panties and take it like a woman cause it doesn't get better until the 6th week when you're all done. And if you have the guts to start all over and treat other areas then you are Super woman. It turns your cells into red blistering raw looking meat that is horrible to look at and worse to feel. But getting rid of the cancer cells is all that matters here. So do it, but be prepared to take time off if needed and be prepared to be miserable.”

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OrdinaryMan December 11, 2019

Aldara (imiquimod) for Human Papilloma Virus: “Got HPV . I did quarterly STD checks and nothing came up. I am half circumcised. It all started with a small white head kind of thingie on internal foreskin and my doctor initially said it could be a protruded sebaceous gland. So didn’t pay much attention. After 2 months that became a small cluster about 5 mm length. Thats when my doctor said its penile wart. I was devastated and got into very low mood for days. Almost thinking about this growth all the time. I was prescribed this drug. After five applications the skin got super sore and blisters appeared with pus. Doctor said that means the cream is working. I had to stop for a week or so because of the scary reaction it had. And in addition even though the warts subsided it grew back. I started applying second round and same reaction occurred after third application. Took a break again but this time the warts magically disappeared. Such a great feeling now!!!!”

9 / 10
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old Iris · Taken for 2 to 5 years November 4, 2018

Aldara (imiquimod) for Basal Cell Carcinoma: “I'm now 82 after 4 surgeries on my face I was given Aldara ..it may make big red ugly areas but with patience it does the job. You may think you just have a small area that is affected but wow..it's usually a larger area than you think. That's why I think it's better that doing the MOH's surgery.”

8 / 10
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Vorn · Taken for 1 to 6 months June 20, 2016

For Basal Cell Carcinoma: “I am using Aladara on 6 sites and would not recommend any more than that. It is about my 4th use of the drug and apart from a slight flu like symptoms when I first started I have suffered no general side effects. I am quite active and still feel energetic enough to run, cycle and play tennis as well as DIY! However the lesions are something else. To give reassurance to anyone using it for the first time the reaction on the skin can be quite alarming BUT is perfectly normal and shows it is working. Do read the leaflet. My neck and behind my ears have reacted severely with heavy scabbing some weeping and painful at night. It is a chore applying and washing off but do persevere. It will all heal within a week of stopping.”

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Anonymous July 21, 2011

Aldara (imiquimod) for Basal Cell Carcinoma: “The side effects of this cream were bad. Very painful sinus, swelling of throat and inside mouth, continuous cough on chest, headache (don't usually suffer headaches, dizziness). May be good for some people but not me. (I am 74).”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.