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Imiquimod topical User Reviews & Ratings (Page 4)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 6.9 out of 10 from a total of 455 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Imiquimod topical

Commonly mentioned side effects
  • mal...
  • Taken for 1 to 6 months
  • October 20, 2019

Imiquimod topical for Human Papilloma Virus "I got HPV despite having safe sex from an erotic massage place. The sample analysis resulted in HPV 16 and 56, which are both high risk. The doctor removed them by cauterization - a horrible process. A year later, I realized I still have a couple of small points. I used Aldiq, which is basically another brand of Aldara made in Italy, and it had great results. With one box - 3 times a week, they almost disappeared. I became a bit obsessed with this, and now I'm checking my penis with a magnifying glass and noticed that there is a little bit of affected tissue which is healing very slowly. Aldara basically made the first layer of the skin dry, and I think it's forcing the area to regenerate. I gave it a 9. Important - I used it Monday, Wednesday, and Friday in the evening after a shower and after I've let my body cool down. I think it's important for the affected area to be inspected with a magnifying glass, which some dermatologists have. Hang in there. It will take some time, but we'll get over it :)"

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • August 18, 2015

For Human Papilloma Virus "I have been using this cream for a month now, and I see results, most of my g warts are gone. It takes time and patience. I know it's an embarrassing disease to have, but there is hope, it's not a death sentence. So far, this cream is working for me. I noticed it does cause irritation if you overdo it, but other than that, I recommend it."

9 / 10
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  • Nod...
  • Taken for less than 1 month
  • April 23, 2016

For Basal Cell Carcinoma "I'm in the UK and on to week 3. I have to apply to a BCC on my chest, but big boils and spots have developed, which are very itchy and weepy, suggesting there were other areas on my chest that need treatment too. I have wanted to stop, as sometimes the itch is so intense and my clothing sticks, but after a positive conversation with a specialist nurse, I am, of course, continuing. I have had the odd flu-like kind of day, and today I am so tired, when I shouldn't be, so I am putting that down to the Aldara cream."

7 / 10
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Frequently asked questions

  • inc...
  • August 20, 2017

Imiquimod topical for Basal Cell Carcinoma "Second time on Aldara. The first time I used it on my right temple, nose, and my face. I was covered in red blotches, like scalds, but I don't remember any severe reactions. I can't seem to remember it hurting, and it was worth it. It cleared the persistent and sore BCC on my nose and temple. I now have another BCC on my forehead which has been persistent and shown no sign of healing and has bled at times. My GP/doctor has prescribed a course of Aldara, and this time I have a much worse reaction. One side of my face has come with very red, swollen spots, blistering, and I have flu-like symptoms. But I am sure it will be worth it."

10 / 10
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  • L B...
  • Taken for less than 1 month
  • November 16, 2014

For Human Papilloma Virus "It works, but it hurts! This is my fourth day using it, and I'm seeing results. The first three days, it itched and made the warts more pronounced and sore (my doctor told me to use it every day and not three times a week.). Today, I've noticed significant changes. A large cluster of about four is gone, but the skin is really irritated. I think there's like three left, but they're not that big. I'm so sore, but at least they're going away. Suggestions: Take a Benadryl before you apply the cream. Decrease the itching, and it'll knock you out. Protect your skin with Vaseline. Get some sterile bandages to cover your 'healing' areas between applications because you will have some... drainage... I guess that's the right word."

8 / 10
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  • Anonymous
  • May 3, 2019

For Human Papilloma Virus "Used imiquimod for HPV (a couple of genital warts) for 1 month at three times a week. After applying 2 times, I started noticing an intense itch/burn in the treated area. Aloe gel would cool and soothe the itch/burn, then started using ice packs, quit using toilet paper, and have a bottle of water to rinse with instead. The itch is everywhere. Started applying Emla cream 2.5% lidocaine to all areas (local anesthetic). Freezing it stops the itch and numbs the burn. Realizing the itch is all new warts coming to the surface. I'm well into my 4th week. Been told 6 weeks use from the day started, but with each continuous outbreak, your 6 weeks starts over. No less than 15, with the hood of my clitoris being the center of about 80% of them. I now use witch hazel, calamine, vitamin E, and a 5% lidocaine med called Jampocaine. I still wake in the night scratching from new ones breaking out. Horrible experience right from the start. Need this to be gone. Huge hit to my confidence. The pain literally consumes me. I even went back to the gyno. He looked, said it's bad, but it's doing its job. So I'm sticking it out."

9 / 10
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  • Ano...
  • April 14, 2015

For Human Papilloma Virus "This cream is one of the most painful and agonizing treatments I have ever received, however, if you are willing to put up with insatiable itching, burning, feeling like you have the flu, and being unable to catch your breath, it is 100% worth it. For me, the few months of pain are worth it to get rid of the embarrassment and self-disgust at having GW. I'm just starting to recover from the treatment and have gone from maybe 30 to around 5 tiny ones (I have an immunity disorder, so I was unable to fight the virus myself and it spread so quickly). Fantastic treatment, absolute agony, but well worth it if you can put up with it."

9 / 10
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More FAQ

  • Anonymous
  • Taken for less than 1 month
  • March 22, 2016

For Human Papilloma Virus "This stuff works for GW. I was diagnosed about three months ago, and I tried acid 3x before to burn them off. It seemed like it irritated them, and more would pop up. Started using this cream 3 weeks ago on MWF nights, and all my GW are gone!!! Other things I think helped were taking an immune system booster supplement, drinking water, and rubbing coconut oil for the in-between days (Tues. Thur.) for the itching and the dryness that the cream causes... All together, I'm pleased with the results, and the side effects weren't any worse than the regular itch that you get from general warts.. Sticking with this routine really helped me, and I hope this is helpful to someone else. GW are not forever!!!"

9 / 10
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  • Pop...
  • January 2, 2020

Imiquimod topical for Human Papilloma Virus "I had a GW 12 days ago, at first, it's small, flat, white warts. So, my OB prescribed me Aldara 3-5 times a day for 10 days and some antibiotics 2 times a day for 10 days. On the 4th day of my application, I felt burning and redness down there until 2 small blisters showed up between the small warts. I also felt side effects similar to the other experience, a fever-like feeling. On the 8th day, the small white wart vanished, but the 2 small blisters still remain. I’m totally freaking out. On the 9th day, 1 blister got bigger and turned out to be white, as well as the other small blister. On the 10th day, when I visited my doctor, she told me to stop the cream and prescribed me multivitamins. She told me to get surgery or burn the warts when I decide. On the 11th day, I stopped using Aldara, but the two white blisters are still there. And still, my V is swollen. I don't know what to do anymore. Will this white blister still go away because I stopped using Aldara already? Any same case as mine? Need help."

6 / 10
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  • Anonymous
  • November 23, 2015

Imiquimod topical for Keratosis "I am a female in my late 60s, and on day 13 of the 1st round of 14. After tomorrow, I will be off 2 weeks and back on for 2 weeks. I am using it on my temples and forehead. Luckily, I have a lot of hair to cover the red spots that have surfaced on my temples. However, I have had NO flu-like symptoms, NO fatigue, NO stomach problems. Nothing... just a bunch of ugly red spots."

8 / 10
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  • Ele...
  • August 20, 2014

For Human Papilloma Virus "For all people who have genital warts, my only advice is: use Aldara cream. It's amazing. I had three warts, one big and two small ones. I went to see the gynecologist, she gave me this cream. After three applications, everything is gone. I don't have any more. However, I still have some of them inside, that's what the pap smear shows. But the inside ones need different therapy. Aldara cleared all my outside warts in one week. Don't hesitate, use it, but you need to check with your doctor if you have other warts inside."

8 / 10
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  • Bre...
  • Taken for less than 1 month
  • July 4, 2014

For Human Papilloma Virus "I was very nervous using this, reading what other people have experienced with side effects. I decided to try it under advisement from my gynecologist. I have 4 small warts. One on my labia, one just inside of it, 2 around my anus. I've been using imiquimod for about 10 days, 3 times a week, 6 hours at a time. In that time, I have seen SIGNIFICANT changes in the 2 on my vaginal area. They are almost completely gone. The other two are being a little more stubborn. I wanted to share some good comments about this medication after being so worried about it myself before. Zero skin irritation. I've had some 'flu-like' symptoms, but nothing unbearable. I'm very happy to see these 'aliens' shrink away. Try it before you knock it!"

10 / 10
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  • Spi...
  • October 25, 2012

For Human Papilloma Virus "This cream really is a miracle. The first few times I used it on my warts, I did not pay attention to only putting it on the warts, I applied it to the general area, and the itching was unbearable. But after paying closer attention to my application, my warts have very noticeably gotten smaller or disappeared after only two weeks of treatment. My side effects were itching, slight sting when applying, slight swelling, and just some overall discomfort. But the side effects were nothing compared to being on a wart-free track!"

8 / 10
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  • Kat...
  • Taken for less than 1 month
  • January 13, 2020

Imiquimod topical for Basal Cell Carcinoma "I treated several areas of my face with Aldara in 2007. My reaction was so severe after 10 days of use that my dermatologist advised me to discontinue the use. I thought I broke my metacarpal, trapezoid, and trapezium. It was swollen and I had such pain I could not even hold a pen. Of course, it had to be my right thumb, and I am right-handed, which is also the hand I applied the cream with. I had an orthopedic friend order an X-ray, which came back as arthritis in those areas. One of the rare side effects, however, I also had fever, chills, malaise, and really ugly inflammation. I have since had to have several lesions surgically removed, involving skin grafts, some removed with the use of liquid nitrogen, and now my dermatologist is recommending I treat them again with Aldara. Not a chance! I will try the Efudex again, however, it did nothing the first time I used it, but that was several years ago, maybe 2000 or earlier."

2 / 10
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  • Gen...
  • Taken for less than 1 month
  • July 26, 2019

Imiquimod topical for Human Papilloma Virus "I had genital warts. I decided to try Aldara and hope for the best. After reading loads of reviews about crazy side effects, I was a bit worried, but my experience has been great. It says to use each sachet only once, but I get at least 3/4 uses out of each. I’ve had no burning and minimal scabbing of the skin, only a slight bit of redness around the affected area. After 2 weeks, the warts began to shrink rapidly and disappeared in the 3rd week! Just ensure you follow the instructions and complete the course (~16 weeks), as I’ve noticed a lot of people have stopped using it once the warts disappear, and then they come back straight away. It cost me £70 for the whole course."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 2, 2020

For Basal Cell Carcinoma "I have had BCC 4 times on top of my nose. One was on top of the nose. I had MOHS, and I had to get a graft from my forehead, which was stitched to the top of my nose and looks terrible. I am so embarrassed to go out. Now, I have a superficial basal cell on the side of the nostril, and my dermatologist gave me Imiquimod cream. The area is getting red, crusty, and scabby. I hope it works as I do not want to have MOH's again. Has anyone ever heard of someone getting basal cell 4 times on the nose?"

7 / 10
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  • Anonymous
  • March 31, 2017

For Basal Cell Carcinoma "I have been using this cream for BCC for 3 weeks, with 1 week left. Apply 3 nights a week. I was not sure what to expect. Using it on my face and neck, initially applied over the entire area until the red areas popped out. Now I'm just using it on the inflamed areas. Almost the entire face is covered in red sores. Very painful, burning, and itchy. Also developed cough and fatigue. Staff at the doctor's office said this was normal. I guess if it has a lot of inflammation, it means it is working. I have wanted to stop the treatment but am trying to stick with it as I'm close to the end. I prefer to not have any additional surgeries. I rarely leave the house, this looks like a contagious disease."

9 / 10
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  • Ano...
  • Taken for less than 1 month
  • March 16, 2018

Imiquimod topical for Molluscum Contagiosum "Had horrific effects from taking this. I'm currently in the process of getting a diagnosis for small fiber neuropathy because of this drug. I was in the best health of my life before I started applying it. Within two days, I had burning sensations all over my body. It caused a systemic reaction. I discontinued immediately, but over two years later, I still get painful burning all over my body. Google Aldara and 'small fiber neuropathy,' and you will see I am not the only one who had this condition triggered by Aldara/imiquimod. This drug is a powerful immunomodulator that triggers multiple types of immune-mediated cells in the body and causes the body to attack itself. People are getting sick from it, and their claims are not being addressed."

1 / 10
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  • Lem...
  • Taken for less than 1 month
  • October 31, 2019

Imiquimod topical for Human Papilloma Virus "I had genital warts on my anus. I was so terrified when I noticed something strange round the back. When I checked through the mirror, there was a small tiny round thing, and I didn't know what it was. I went directly to check on Google what it was, and I got shocked! I have been so depressed knowing that I have genital warts. I went to the dermatologist, and he did cryotherapy, it worked. Around 3 days, my small tiny thing was gone. I had sexual intercourse, and it came back. I didn't tell my dermatologist, but he told me that it may come back, so he prescribed Aldara to me for 3 weeks every other day. And now I'm 2 years wart-free. This product really works. No pain. No hassle."

9 / 10
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  • Anonymous
  • January 19, 2012

Imiquimod topical for Keratosis "I took Zyclara for the first time a year ago at the age of 34 after my doctor froze off 3 actinic keratosis. Actinic keratosis on my nose is back, also, I still have red spots where lesions were during the initial treatment. Doctor says I need another round to finish off the damage and as a last best hope to avoid having to surgically remove the spot on my nose. I have fair skin and tons of sun damage (including 2nd-degree burns over 20% of my body). My doctor initially recommended that I take 2 months off for the treatment, this time, I will take her advice! I found the treatment too intense to work through due to pain and fatigue. Moisturizing the area with petroleum jelly and a topical anesthetic and antimicrobial (Neosporin or Polysporin) helped a lot!"

8 / 10
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  • Mc0...
  • June 21, 2015

For Basal Cell Carcinoma "I'm using this for BCC. My areas were small to begin with. I am on week 6 and was instructed to use it 5 times a week. I've used a very small amount, and I haven't had severe side effects. My lymph nodes have been swollen a few times. I make sure to wash the areas, let them dry, wash my hands, and apply. I have always washed it off 8 hours later. I've also avoided getting in the sun. The areas haven't disappeared yet, and I'm not sure what they should look like at this point."

9 / 10
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  • Nor...
  • Taken for less than 1 month
  • November 30, 2016

For Human Papilloma Virus "Imiquimod is amazing! I found out I had HPV last week, and I had one small wart plus some textured areas where it seemed as if more were forming. I was prescribed Imiquimod, and one week later, all of the texture is gone, the area is smooth, and the one raised small wart is pretty much gone! I had no side effects other than a little sensitivity and 'rawness' on the site of application, but totally worth it. However, I have been taking very good care of myself: eating well and getting sufficient rest, so I can boost my immune system to help fight the outbreak. It's nice to feel back to 'normal.'"

10 / 10
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  • Hap...
  • Taken for less than 1 month
  • December 16, 2016

For Human Papilloma Virus "So, I have to admit I was really surprised when I was diagnosed with HPV. I had had two sexual partners, kept up to date on regular Pap tests, and even received the most recent vaccines against the virus (Gardasil 9). But it happened. I found one abnormality inside my vaginal opening. It didn't even really look like a wart, it was so small. But it wasn't there before. So I went in to see my doctor, and yep, low-risk HPV. Prescribed Aldara. I was told to apply it daily for one week. After the first four applications, it was almost gone! Very happy. But because of the location, it chemically burned my skin in nearby areas. Very painful. But it works! I also eat healthy and take vitamins. My boyfriend was incredibly supportive as well."

9 / 10
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  • abc...
  • April 11, 2021

Imiquimod topical for Human Papilloma Virus "Always wondered if I would ever get to leave a review on here. After 8 months, I finally stopped using Aldara. To be honest, I don't even know if it was the cream or just time that got rid of the warts. I never had a huge outbreak, but they were stubborn. It started with two bigger ones. They decreased in size after using the cream but never really went away. I ripped most of them off, to be honest. I know how you guys feel. I was severely depressed during this time. Side effects were nonexistent in the beginning, but after some time they were horrible: my skin got so thin that it ripped all the time (I mean huge tears like after giving birth), I've had constant yeast infections and couldn't pee without being in pain (put your hands on the floor while peeing, thank me later). I don't want to scare anyone, but I was fooled by reviews that promised me that it would all be gone after a month. You're normal, not alone, and you will eventually fight it."

5 / 10
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  • AAS...
  • January 30, 2018

Imiquimod topical for Basal Cell Carcinoma "Easy to apply. The medication journal makes it easy to track usage and clearly defines “break days.” This is week four. Skin is red and irritated, however very bearable and annoying rather than painful. Other side effects are pretty hard to tolerate. Fatigue is beyond belief and at times debilitating, yet unable to sleep. Nausea all the time. Headache at times. Perception seems to be a little distorted. Difficult to tell how much the light-headed feeling is coming from fatigue. Joints ache. A little weight gain. I’m irritable due to unbearable fatigue. Dreams at night are emotionally overwhelming and vivid. The effect of alcohol is extremely magnified. I call these my little bottles of hell. That’s how they make me feel. That said, it seems to be working, and I’m very interested in seeing the results. Given a choice at this stage, excision would be my preference. That might change by the time I finish treatment. However, it would take a lot to endure this again."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.