What is Fluoroplex?
Fluoroplex (for the skin) is used to treat scaly overgrowths of skin (actinic or solar keratosis).
Fluoroplex is also used to treat superficial basal cell carcinoma.
Fluoroplex may also be used for purposes not listed in this medication guide.
Fluoroplex side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Fluoroplex may cause serious side effects. Stop using Fluoroplex and call your doctor at once if you have:
severe pain or swelling of treated skin;
severe itching, burning, or irritation;
new or worsening skin sores;
fever, chills; or
Before your skin begins to heal it will become red, dry, tender, and crusty. This is a normal skin reaction, even if these symptoms get worse for a short time. Gradually, the dead skin will begin to shed off and you'll see raw skin appear. Ask your doctor when to stop using the medicine after you notice signs of healing.
Common side effects of Fluoroplex may include:
skin pain, itching, burning, or irritation;
skin darkening or scarring;
skin redness and swelling; or
small blood vessels under the skin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Before taking this medicine
You should not use Fluoroplex if you are allergic to fluorouracil, or if you have:
a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency.
Do not use Fluoroplex if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.
You should not breastfeed while using Fluoroplex.
Fluoroplex is not approved for use by anyone younger than 18 years old.
How should I use Fluoroplex?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Do not take by mouth. Topical medicine is for use only on the skin.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Wash your hands before and immediately after applying this medicine, unless it is being used to treat a hand condition. Caregivers who apply this medicine should wear rubber gloves.
Apply only enough medicine to cover the affected skin with a thin film. Do not cover the treated skin area with bandaging or plastic unless your doctor tells you to.
Do not apply Fluoroplex to skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using this medicine.
You may need to use Fluoroplex for up to 6 weeks. Treated skin may have an undesirable appearance as it heals, which may take several weeks.
Store at room temperature away from moisture and heat. Do not freeze. Keep the medicine container tightly closed when not in use. Keep out of the reach of children and pets.
Do not use Fluoroplex to treat a skin condition that has not been checked by your doctor.
What happens if I miss a dose?
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Fluoroplex?
Do not use Fluoroplex on your eyelids or in your eyes, nose, or mouth. Rinse with water or saline if this medicine gets in your eyes.
Do not let Fluoroplex build up in the skin folds around your mouth, nose, or eyes. Use caution when applying the medicine around these areas.
Avoid using other medications on the areas you treat with fluorouracil unless your doctor tells you to.
What other drugs will affect Fluoroplex?
Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.
More about Fluoroplex (fluorouracil topical)
- Compare alternatives
- Pricing & coupons
- Reviews (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: topical antineoplastics
- En español
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2023 Cerner Multum, Inc. Version: 6.01.