Fluoroplex Side Effects
Generic name: fluorouracil topical
Medically reviewed by Drugs.com. Last updated on Sep 7, 2023.
Note: This document provides detailed information about Fluoroplex.
Applies to fluorouracil topical: topical cream, topical solution Side Effects associated with fluorouracil topical. Some dosage forms listed on this page may not apply specifically to the brand name Fluoroplex.
Applies to fluorouracil topical: topical cream, topical solution.
Precautions
It is very important that your doctor check your progress at regular visits for any unwanted effects that may be caused by this medicine.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment. If you think you have become pregnant while using the medicine, tell your doctor right away.
This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds. If you have a severe reaction from the sun, check with your doctor.
This medicine may cause black, tarry stools, blurred or double vision, chills, cough, diarrhea, difficulty in walking, drooping eyelids, fever, headache, jaw pain, lower back or side pain, numbness or tingling in the fingers and toes, pain in the fingers, toes, and testicles, painful or difficult urination, pale skin, sore throat, sores, ulcers, or white spots in the mouth or on the lips, swelling or inflammation of the mouth, unusual bleeding or bruising, or unusual tiredness or weakness. Check with your doctor right away if you notice any of these serious side effects.
Serious side effects of Fluoroplex
Along with its needed effects, fluorouracil topical (the active ingredient contained in Fluoroplex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fluorouracil topical:
Incidence not known
- black, tarry stools
- bleeding gums
- blood in the urine or stools
- chest pain
- chills
- cough
- fever
- painful or difficult urination
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- swollen glands
- trouble breathing
- unusual bleeding or bruising
- unusual tiredness or weakness
Other side effects of Fluoroplex
Some side effects of fluorouracil topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- dry, rough, or scaly skin
- loss or thinning of the hair
- raised, dark red, wart-like spots on the skin, especially when used on the face
- swelling or inflammation of the mouth
- tearing of the eyes
- trouble sleeping
For healthcare professionals
Applies to fluorouracil topical: topical cream, topical kit, topical solution.
Dermatologic adverse events
- Very rare (less than 0.01%): Pruritus, urticaria, rash (local or generalized), erythema (i.e., erythema multiforme), burning sensation, exfoliation, swelling, ulceration, allergic contact dermatitis, eczema, blistering, alopecia, pain
- Frequency not reported: Hyperpigmentation, crusting, irritation, photosensitivity, scarring, bullous pemphigoid, ichthyosis, scaling, suppuration, telangiectasia, tenderness, herpes simplex[Ref]
Gastrointestinal
- Very rare (less than 0.01%): Diarrhea, vomiting, abdominal pain, stomatitis, mucosal inflammation
- Frequency not reported: Nausea, medicinal taste[Ref]
Hematologic
- Frequency not reported: Leukocytosis, eosinophilia, thrombocytopenia, toxic granulation[Ref]
Hypersensitivity
- Very rare (less than 0.01%): Hypersensitivity[Ref]
Nervous system
- Frequency not reported: Dysgeusia, headache, dizziness[Ref]
Ocular
- Frequency not reported: Conjunctival irritation, corneal reaction, keratitis, increased lacrimation[Ref]
Other
- Very rare (less than 0.01%): Pyrexia, chills[Ref]
Respiratory
- Frequency not reported: Nasal irritation[Ref]
Psychiatric
See also:
Voltaren Arthritis Pain Gel
Voltaren Arthritis Pain Gel (diclofenac topical) is used to treat joint pain in the hands, wrists ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Efudex
Efudex is used for actinic keratosis, basal cell carcinoma, keratosis, skin cancer
Aldara
Aldara (imiquimod) is used to treat actinic keratosis, basal cell carcinoma and genital warts ...
Pennsaid
Pennsaid (diclofenac sodium topical solution) is used to treat osteoarthritis of the knee. Includes ...
Klisyri
Klisyri (tirbanibulin) is used for the topical treatment of actinic keratosis on the face and ...
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. Cerner Multum, Inc. "Australian Product Information."
3. (2017) "Product Information. Fluorouracil Topical (fluorouracil topical)." A-S Medication Solutions
4. (2017) "Product Information. Tolak (fluorouracil topical)." Hill Dermaceuticals Inc
5. (2017) "Product Information. Efudex (fluorouracil topical)." Valeant Pharmaceuticals
6. (2017) "Product Information. Fluoroplex (fluorouracil topical)." Aqua Pharmaceuticals LLC
More about Fluoroplex (fluorouracil topical)
- Check interactions
- Compare alternatives
- Reviews (2)
- Dosage information
- During pregnancy
- Drug class: topical antineoplastics
- Breastfeeding
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
Further information
Fluoroplex side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.