Dextrostat Side Effects
Generic name: dextroamphetamine
Medically reviewed by Drugs.com. Last updated on Jul 28, 2023.
Note: This document contains side effect information about dextroamphetamine. Some dosage forms listed on this page may not apply to the brand name Dextrostat.
Applies to dextroamphetamine: transdermal patch extended release. Other dosage forms:
Warning
Transdermal route (Patch, Extended Release)
Abuse, Misuse, and AddictionDextroamphetamine has a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including dextroamphetamine, can result in overdose and death, and this risk is increased with higher doses or unapproved methods of administration, such as snorting or injection.Before prescribing dextroamphetamine, assess each patient’s risk for abuse, misuse, and addiction. Educate patients and their families about these risks, proper storage of the drug, and proper disposal of any unused drug. Throughout dextroamphetamine treatment, reassess each patient’s risk of abuse, misuse, and addiction and frequently monitor for signs and symptoms of abuse, misuse, and addiction.
Serious side effects of Dextrostat
Along with its needed effects, dextroamphetamine (the active ingredient contained in Dextrostat) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking dextroamphetamine:
More common
- Black, tarry stools
- chills
- cough
- fever
- lower back or side pain
- painful or difficult urination
- pale skin
- sore throat
- trouble breathing
- ulcers, sores, or white spots in the mouth
- unusual bleeding or bruising
- unusual tiredness or weakness
Less common
- Increased heart rate
- increase in blood pressure
Incidence not known
- Anger
- bladder pain
- blistering, burning, crusting, dryness, flaking, peeling, or loosening of the skin
- bloody nose
- bloody or cloudy urine
- bloody vomit
- blurred vision
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chest pain, discomfort, or tightness
- dark urine
- delusions of persecution, mistrust, suspiciousness, or combativeness
- diarrhea
- difficulty in speaking
- discouragement
- dizziness
- fast, slow, pounding, or irregular heartbeat or pulse
- fear, nervousness
- feeling sad or empty
- frequent urge to urinate
- hives, itching, skin rash
- irritability
- joint or muscle pain
- lack of appetite
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- light-colored stools
- loss of interest or pleasure
- mood swings
- muscle cramps, spasms, pain, or stiffness
- nausea
- pain or discomfort in the arms, jaw, back, or neck
- paleness or cold feeling in the fingertips and toes
- pounding in the ears
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red irritated eyes
- red skin lesions, often with a purple center
- restlessness
- scaling, severe redness, soreness, or swelling of the skin
- seizures
- severe stomach pain
- shakiness in the legs, arms, hands, or feet
- sleepiness or unusual drowsiness
- sweating
- swelling of the feet or lower legs
- tingling or pain in the fingers or toes when exposed to cold
- trembling or shaking of the hands or feet
- trouble concentrating
- trouble sleeping
- twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
- upper right abdominal or stomach pain
- vomiting
- weight decreased
- yellow eyes and skin
Get emergency help immediately if any of the following symptoms of overdose occur while taking dextroamphetamine:
Symptoms of overdose
- Aggressive
- agitation
- angry
- blurred vision
- change in consciousness
- chest pain or discomfort
- confusion
- diarrhea
- dark urine
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fainting
- fast breathing
- fast, slow, or irregular heartbeat
- fever
- headache
- inability to speak
- loss of consciousness
- muscle cramps, spasms, pain, or stiffness
- nausea
- nervousness
- overactive reflexes
- pain or discomfort in the arms, jaw, back, or neck
- pale, clammy skin
- palpitations
- pounding in the ears
- restlessness
- seeing, hearing, or feeling things that are not there
- seizures
- shivering
- slow or fast heartbeat
- slurred speech
- stomach cramps
- sweating
- talking or acting with excitement you cannot control
- temporary blindness
- thirst
- tremor
- trouble breathing
- unusual tiredness or weakness
- vomiting
Other side effects of Dextrostat
Some side effects of dextroamphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Decreased appetite
- headache
Incidence not known
- Bigger, dilated, or enlarged pupils (black part of eye)
- change in taste
- constipation
- decreased interest in sexual intercourse
- double vision
- inability to have or keep an erection
- increased sensitivity of the eyes to light
- loss in sexual ability, desire, drive, or performance
- loss of taste
- loss or thinning of the hair
- seeing double
For Healthcare Professionals
Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet, transdermal film.
Metabolic
Very common (10% or more): Decreased appetite, reduced weight gain, weight loss
Common (1% to 10%): Anorexia
Frequency not reported: Acidosis[Ref]
Psychiatric
Very common (10% or more): Insomnia, nervousness
Common (1% to 10%): Abnormal behavior, aggression/hostility, excitation, anxiety, depression, irritability
Uncommon (0.1% to 1%): Psychotic episodes/psychosis
Very rare (less than 0.01%): Suicidal behavior (including completed suicide), mania, hallucinations
Frequency not reported: Overstimulation, restlessness, euphoria, dysphoria, confusion, dependence, emotional lability, impaired cognitive test performance, altered libido, night terrors, obsessive-compulsive behavior, panic states, paranoia[Ref]
Cardiovascular
Common (1% to 10%): Arrhythmia, palpitations, tachycardia
Rare (less than 0.1%): Angina pectoris
Very rare (less than 0.01%): Cardiac arrest
Frequency not reported: Blood pressure and heart rate changes (usually elevated), cardiomyopathy, myocardial infarction, chest pain, cardiovascular collapse, Raynaud's phenomenon[Ref]
Gastrointestinal
Common (1% to 10%): Abdominal pain and cramps, nausea, vomiting, dry mouth
Frequency not reported: Ischemic colitis, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances[Ref]
Musculoskeletal
Common (1% to 10%): Arthralgia
Rare (less than 0.1%): Growth retardation
Very rare (less than 0.01%): Muscle cramps
Frequency not reported: Rhabdomyolysis[Ref]
Nervous system
Common (1% to 10%): Vertigo, dyskinesia, headache, hyperactivity
Very rare (less than 0.01%): Tourette syndrome, tics, exacerbation of pre-existing motor and phonic tics, convulsions, choreoathetoid movements, intracranial hemorrhage, cerebral vasculitis and/or occlusion, neuroleptic malignant syndrome (NMS)
Frequency not reported: Dizziness, tremor, ataxia, dysgeusia, concentration difficulties, hyperreflexia, stroke[Ref]
Dermatologic
Rare (less than 0.1%): Rash, urticaria
Very rare (less than 0.01%): Erythema multiforme, exfoliative dermatitis, fixed drug eruption
Frequency not reported: Sweating, alopecia[Ref]
Ocular
Rare (less than 0.1%): Visual accommodation difficulties, blurred vision, mydriasis[Ref]
Other
Rare (less than 0.1%): Fatigue
Frequency not reported: Hyperpyrexia, sudden death[Ref]
Hematologic
Very rare (less than 0.01%): Anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura[Ref]
Hepatic
Very rare (less than 0.01%): Abnormal liver function ranging from hepatic enzyme elevations to hepatic coma[Ref]
Endocrine
Frequency not reported: Impotence, libido changes, frequent or prolonged erections[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions (e.g., angioedema and anaphylaxis)[Ref]
Renal
Frequency not reported: Renal damage[Ref]
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More about Dextrostat (dextroamphetamine)
- Check interactions
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- Latest FDA alerts (3)
- Dosage information
- During pregnancy
- Drug class: CNS stimulants
- Breastfeeding
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References
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
2. Cerner Multum, Inc. Australian Product Information.
3. Product Information. Dexedrine (dextroamphetamine). SmithKline Beecham. 2001;PROD.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.