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The following information is not a substitute for the knowledge and judgement of a healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Always consult with your doctor, nurse, or pharmacist before taking medication.

Dextroamphetamine Side Effects

For the Consumer

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet

In addition to its needed effects, some unwanted effects may be caused by dextroamphetamine. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking dextroamphetamine:

Rare Incidence not known:

If any of the following symptoms of overdose occur while taking dextroamphetamine, get emergency help immediately:

Symptoms of overdose:

Minor Side Effects

Some of the side effects that can occur with dextroamphetamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:

For Healthcare Professionals

Applies to dextroamphetamine: oral capsule extended release, oral solution, oral tablet

Metabolic

Very common (10% or more): Decreased appetite, reduced weight gain, weight loss
Common (1% to 10%): Anorexia
Frequency not reported: Acidosis[Ref]

Psychiatric

Very common (10% or more): Insomnia, nervousness
Common (1% to 10%): Abnormal behavior, aggression/hostility, excitation, anxiety, depression, irritability
Uncommon (0.1% to 1%): Psychotic episodes/psychosis
Very rare (less than 0.01%): Suicidal behavior (including completed suicide), mania, hallucinations
Frequency not reported: Overstimulation, restlessness, euphoria, dysphoria, confusion, dependence, emotional lability, impaired cognitive test performance, altered libido, night terrors, obsessive-compulsive behavior, panic states, paranoia[Ref]

Cardiovascular

Common (1% to 10%): Arrhythmia, palpitations, tachycardia
Rare (less than 0.1%): Angina pectoris
Very rare (less than 0.01%): Cardiac arrest
Frequency not reported: Blood pressure and heart rate changes (usually elevated), cardiomyopathy, myocardial infarction, chest pain, cardiovascular collapse, Raynaud's phenomenon[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain and cramps, nausea, vomiting, dry mouth
Frequency not reported: Ischemic colitis, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia
Rare (less than 0.1%): Growth retardation
Very rare (less than 0.01%): Muscle cramps
Frequency not reported: Rhabdomyolysis[Ref]

Nervous system

Common (1% to 10%): Vertigo, dyskinesia, headache, hyperactivity
Very rare (less than 0.01%): Tourette syndrome, tics, exacerbation of pre-existing motor and phonic tics, convulsions, choreoathetoid movements, intracranial hemorrhage, cerebral vasculitis and/or occlusion, neuroleptic malignant syndrome (NMS)
Frequency not reported: Dizziness, tremor, ataxia, dysgeusia, concentration difficulties, hyperreflexia, stroke[Ref]

Dermatologic

Rare (less than 0.1%): Rash, urticaria
Very rare (less than 0.01%): Erythema multiforme, exfoliative dermatitis, fixed drug eruption
Frequency not reported: Sweating, alopecia[Ref]

Ocular

Rare (less than 0.1%): Visual accommodation difficulties, blurred vision, mydriasis[Ref]

Other

Rare (less than 0.1%): Fatigue
Frequency not reported: Hyperpyrexia, sudden death[Ref]

Hematologic

Very rare (less than 0.01%): Anemia, leukopenia, thrombocytopenia, thrombocytopenic purpura[Ref]

Hepatic

Very rare (less than 0.01%): Abnormal liver function ranging from hepatic enzyme elevations to hepatic coma[Ref]

Endocrine

Frequency not reported: Impotence, libido changes, frequent or prolonged erections[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions (e.g., angioedema and anaphylaxis)[Ref]

Renal

Frequency not reported: Renal damage[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Dexedrine (dextroamphetamine)" SmithKline Beecham, Philadelphia, PA.

Not all side effects for dextroamphetamine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about dextroamphetamine

Consumer resources

Other brands: Dexedrine, Zenzedi, Dextrostat, ProCentra, Liquadd

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.