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Desoxyn Side Effects

Generic Name: methamphetamine

Note: This document contains side effect information about methamphetamine. Some of the dosage forms listed on this page may not apply to the brand name Desoxyn.

For the Consumer

Applies to methamphetamine: oral tablet


Oral route (Tablet)

Methamphetamine has a high potential for abuse and it should be tried only in weight reduction programs for patients in whom alternative therapy has been ineffective. Administration for prolonged periods of time in obesity may lead to drug dependence and must be avoided.

Along with its needed effects, methamphetamine (the active ingredient contained in Desoxyn) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking methamphetamine:


  • Agitation
  • delusions
  • hallucinations

Incidence Not Known

  • Blurred vision
  • chest discomfort or pain
  • dark-colored urine
  • difficulty breathing
  • dizziness
  • faintness
  • false or unusual sense of wellbeing
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • headache
  • muscle cramps or spasms
  • muscle pain or stiffness
  • pounding in the ears
  • restlessness
  • shakiness in the legs, arms, hands, or feet
  • swelling of the feet or lower legs
  • trembling or shaking of the hands or feet
  • trouble sleeping
  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • uncontrolled vocal outbursts and tics
  • unusual tiredness or weakness

Some side effects of methamphetamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence Not Known

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • constipation
  • decreased interest in sexual intercourse
  • dry mouth
  • hives or welts, itching, or skin rash
  • inability to have or keep an erection
  • indigestion
  • loss in sexual ability, desire, drive, or performance
  • passing of gas
  • redness of the skin
  • weight loss

For Healthcare Professionals

Applies to methamphetamine: oral tablet, oral tablet extended release


Frequency not reported: Elevated blood pressure, tachycardia, palpitation, fatal cardiorespiratory arrest

Postmarketing reports: Peripheral vasculopathy[Ref]


Frequency not reported: Rhabdomyolysis, growth suppression[Ref]


Rare (less than 0.1%): Psychotic episodes

Frequency not reported: Dysphoria, euphoria, insomnia, restlessness[Ref]

Nervous system

Frequency not reported: Dizziness, overstimulation, tremor, headache, exacerbation of motor/phonic tics and Tourette's syndrome[Ref]


Frequency not reported: Diarrhea, constipation, dry mouth, unpleasant taste, other GI disturbances[Ref]


Frequency not reported: Impotence, libido changes, frequent or prolonged erections[Ref]


Frequency not reported: Urticaria[Ref]


1. "Product Information. Desoxyn (methamphetamine)" Abbott Pharmaceutical, Abbott Park, IL.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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