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Daridorexant Side Effects

Medically reviewed by Drugs.com. Last updated on Jul 27, 2023.

Applies to daridorexant: oral tablet.

Serious side effects of daridorexant

Along with its needed effects, daridorexant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking daridorexant:

More common side effects

  • relaxed and calm
  • sleepiness
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusually deep sleep
  • unusually long duration of sleep

Incidence not known

  • changes in behavior
  • discouragement
  • feeling sad or empty
  • hives, itching, skin rash
  • irritability
  • lack of appetite
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of interest or pleasure
  • seeing, hearing, or feeling things that are not there
  • thoughts of killing oneself
  • trouble concentrating

Other side effects of daridorexant

Some side effects of daridorexant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • dizziness
  • feeling of constant movement of self or surroundings
  • headache
  • nausea
  • sensation of spinning

Managing side effects (general information)

For healthcare professionals

Applies to daridorexant: oral tablet.

General adverse events

The most common adverse reactions were headache, somnolence, and fatigue.[Ref]

Gastrointestinal

Nausea includes nausea, vomiting and procedural nausea.[Ref]

Hypersensitivity

Postmarketing: Hypersensitivity, angioedema, rash, urticaria[Ref]

Nervous system

Headache includes headache, tension headache, migraine with and without aura and head discomfort.

Dizziness includes, dizziness, vertigo and labyrinthitis.[Ref]

Psychiatric

Postmarketing: Nightmares, abnormal dreams[Ref]

Somnolence or fatigue includes somnolence, sedation, fatigue, hypersomnia and lethargy.[Ref]

References

1. (2024) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals UK Ltd

2. (2024) "Product Information. Quviviq (daridorexant)." Idorsia Pharmaceuticals US Inc., SUPPL-12

Frequently asked questions

Further information

Daridorexant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer