Cyclizine Side Effects
Applies to cyclizine: oral tablet, oral tablet chewable
Nervous system
Paralysis was reported with IV formulations and typically affected the limbs within minutes of administration. This side effect usually resolved within hours following discontinuation of treatment.[Ref]
Rare (0.01% to 0.1%): Depressed levels of consciousness, loss of consciousness
Frequency not reported: Convulsions, coordination abnormal, decreased consciousness, dizziness, drowsiness, dyskinesia, dystonia, extrapyramidal motor disturbances, generalized chorea, headaches, incoordination, paralysis, paresthesia, somnolence, transient speech disorders, tremor[Ref]
Other
Rare (0.01% to 0.1%): Chills, sensation of heaviness
Frequency not reported: Asthenia, pain, tinnitus[Ref]
Dermatologic
Rare (0.01% to 0.1%): Pruritus
Frequency not reported: Allergic skin reaction, blisters, drug rash, erythema, fixed drug eruption, photosensitivity reaction, urticaria[Ref]
Gastrointestinal
Frequency not reported: Abdominal pain upper, constipation, diarrhea, dry mouth, duodenogastric reflux, increased gastric reflux, nausea, stomach pain, vomiting[Ref]
Psychiatric
Frequency not reported: Agitation, auditory and visual hallucinations, disorientation, euphoria, insomnia, nervousness, Restlessness[Ref]
Auditory and visual hallucinations were reported, especially at doses exceeding recommendations.[Ref]
Cardiovascular
Frequency not reported: Arrhythmias, hypertension, hypotension, palpitations, tachycardia, thrombophlebitis, vein tracking[Ref]
Respiratory
Frequency not reported: Apnea, bronchospasm, dry nose, dry throat[Ref]
Hepatic
Frequency not reported: Cholestatic hepatitis, cholestatic jaundice, hypersensitivity hepatitis, liver dysfunction[Ref]
Hematologic
Frequency not reported: Agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia[Ref]
Local
Injection site reactions included blisters, erythema, pain, thrombophlebitis, and vein tracking.[Ref]
Frequency not reported: Injection site erythema, injection site pain, injection site reactions[Ref]
Hypersensitivity
Anaphylaxis occurred with concomitant propanidid given via IV administration in the same syringe.[Ref]
Frequency not reported: Anaphylaxis, angioedema, hypersensitivity reactions[Ref]
Metabolic
Frequency not reported: Decreased appetite, loss of appetite[Ref]
Musculoskeletal
Frequency not reported: Muscle spasms, twitching[Ref]
Ocular
Frequency not reported: Blurred vision, oculogyric crisis[Ref]
Genitourinary
Frequency not reported: Urinary retention[Ref]
References
1. "Product Information. Bonine For Kids (cyclizine)." Heritage/Insight Consumer Products, Plymouth, PA.
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about cyclizine
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- 14 Reviews
- Drug class: anticholinergic antiemetics
