Cyclizine Dosage

Usual Adult Dose for Motion Sickness

50 mg orally 30 minutes prior to departure. The dosage may be repeated every 4 to 6 hours, not to exceed 200 mg/24 hours.

Usual Adult Dose for Nausea/Vomiting

50 mg orally or intramuscularly every 4 to 6 hours as needed.
The daily dose should not exceed 200 mg.

Usual Pediatric Dose for Motion Sickness

13 to 18 years: 50 mg orally up to 4 times a day.
6 to 12 years: 25 mg orally up to 3 times a day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Cyclizine used for prevention of motion sickness should be administered 30 minutes prior to travel and continued for the duration of exposure.

Because of the anticholinergic action of this agent, use with caution and with appropriate monitoring in patients with glaucoma, obstructive disease of the GI or GU tract and in elderly males with possible prostatic hypertrophy. This drug may have a hypotensive action, which may be confusing or dangerous in postoperative patients.