Cleviprex Side Effects

Generic Name: clevidipine

Note: This document contains side effect information about clevidipine. Some of the dosage forms listed on this page may not apply to the brand name Cleviprex.

For the Consumer

Applies to clevidipine: intravenous emulsion

Along with its needed effects, clevidipine (the active ingredient contained in Cleviprex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:

• Agitation
• confusion
• decreased urine output
• depression
• dizziness
• fainting
• fast or irregular heartbeat
• headache
• hostility
• irritability
• lethargy
• loss of consciousness
• muscle twitching
• nausea
• rapid weight gain
• seizures (convulsions)
• stupor
• swelling of the face, ankles, or hands
• unusual tiredness or weakness

• Chest pain or discomfort
• difficult or labored breathing
• pain or discomfort in the arms, jaw, back, or neck
• shortness of breath
• stopping of the heart
• sweating
• tightness in the chest
• unconsciousness
• very low blood pressure or pulse
• vomiting
• wheezing

For Healthcare Professionals

Applies to clevidipine: intravenous emulsion

Cardiovascular

Cardiovascular side effects have included atrial fibrillation (up to 21%), myocardial infarction (less than 1%), cardiac arrest (less than 1%), systemic hypotension, and reflex tachycardia. Hypotension and reflex tachycardia have been reported during postmarketing experience.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea (up to 21%) and vomiting (3.2%). Ileus and nausea have been reported during postmarketing experience.^[Ref]

Renal

Renal side effects have included acute renal failure (up to 9%).^[Ref]

Nervous system

Nervous system side effects have included headache (6.3%) and syncope (less than 1%).^[Ref]

Respiratory

Respiratory side effects have included dyspnea (less than 1%).^[Ref]

Other

Other side effects have included decreased oxygen saturation (possible pulmonary shunting) during postmarketing experience.

Metabolic

Metabolic side effects have included increased blood triglycerides during postmarketing experience.

Hypersensitivity

Hypersensitivity side effects have included hypersensitivity during postmarketing experience.

Some side effects of Cleviprex may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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