Cleviprex Side Effects
Generic name: clevidipine
Medically reviewed by Drugs.com. Last updated on Oct 19, 2024.
Note: This document provides detailed information about Cleviprex Side Effects associated with clevidipine. Some dosage forms listed on this page may not apply specifically to the brand name Cleviprex.
Applies to clevidipine: intravenous emulsion.
Precautions
Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to another medicine that works the same way. If you have any concerns about this, talk to your doctor.
Serious side effects of Cleviprex
Along with its needed effects, clevidipine (the active ingredient contained in Cleviprex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:
More common side effects
- agitation
- confusion
- decreased urine output
- depression
- dizziness
- fainting
- fast or irregular heartbeat
- headache
- hostility
- irritability
- lethargy
- loss of consciousness
- muscle twitching
- nausea
- rapid weight gain
- seizures (convulsions)
- stupor
- swelling of the face, ankles, or hands
- unusual tiredness or weakness
Rare side effects
- chest pain or discomfort
- difficult or labored breathing
- pain or discomfort in the arms, jaw, back, or neck
- shortness of breath
- stopping of the heart
- sweating
- tightness in the chest
- unconsciousness
- very low blood pressure or pulse
- vomiting
- wheezing
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For healthcare professionals
Applies to clevidipine: intravenous emulsion.
General adverse events
Atrial fibrillation, sinus tachycardia, and hypotension were frequently observed in the perioperative population.[Ref]
Cardiovascular
- Very common (10% or more): Atrial fibrillation (up to 32.9%), sinus tachycardia (up to 30.5%), hypotension (up to 15.1%)
- Common (1% to 10%): Flushing
- Uncommon (0.1% to 1%): Atrial flutter, tachycardia, congestive heart failure, bradycardia, complete atrioventricular block, bundle branch block
- Frequency not reported: Myocardial infarction, cardiac arrest
- Postmarketing reports: Reflex tachycardia[Ref]
Gastrointestinal
- Very common (10% or more): Nausea (up to 21%)
- Common (1% to 10%): Vomiting
- Uncommon (0.1% to 1%): Constipation
- Rare (less than 0.1%): Ileus[Ref]
Nervous system
Other
- Common (1% to 10%): Edema, chest pain, feeling hot[Ref]
Metabolic
- Common (1% to 10%): Oxygen saturation decreased
- Postmarketing reports: Blood triglycerides increased[Ref]
Renal
- Common (1% to 10%): Acute renal failure[Ref]
Genitourinary
- Common (1% to 10%): Polyuria[Ref]
Respiratory
- Uncommon (0.1% to 1%): Pulmonary congestion
- Frequency not reported: Dyspnea[Ref]
Immunologic
- Uncommon (0.1% to 1%): Hypersensitivity[Ref]
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. (2008) "Product Information. Cleviprex (clevidipine)." The Medicines Company
More about Cleviprex (clevidipine)
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- Drug class: calcium channel blockers
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Further information
Cleviprex side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.