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Cleviprex Side Effects

Generic name: clevidipine

Medically reviewed by Last updated on Nov 2, 2023.

Note: This document contains side effect information about clevidipine. Some dosage forms listed on this page may not apply to the brand name Cleviprex.

Applies to clevidipine: intravenous emulsion.

Serious side effects of Cleviprex

Along with its needed effects, clevidipine (the active ingredient contained in Cleviprex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:

More common

  • Agitation
  • confusion
  • decreased urine output
  • depression
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • headache
  • hostility
  • irritability
  • lethargy
  • loss of consciousness
  • muscle twitching
  • nausea
  • rapid weight gain
  • seizures (convulsions)
  • stupor
  • swelling of the face, ankles, or hands
  • unusual tiredness or weakness


For Healthcare Professionals

Applies to clevidipine: intravenous emulsion.


Atrial fibrillation, sinus tachycardia, and hypotension were frequently observed in the perioperative population.[Ref]


Very common (10% or more): Atrial fibrillation (up to 32.9%), sinus tachycardia (up to 30.5%), hypotension (up to 15.1%)

Common (1% to 10%): Flushing

Uncommon (0.1% to 1%): Atrial flutter, tachycardia, congestive heart failure, bradycardia, complete atrioventricular block, bundle branch block

Frequency not reported: Myocardial infarction, cardiac arrest

Postmarketing reports: Reflex tachycardia[Ref]


Very common (10% or more): Nausea (up to 21%)

Common (1% to 10%): Vomiting

Uncommon (0.1% to 1%): Constipation

Rare (less than 0.1%): Ileus[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness

Frequency not reported: Syncope[Ref]


Common (1% to 10%): Edema, chest pain, feeling hot[Ref]


Common (1% to 10%): Oxygen saturation decreased

Postmarketing reports: Blood triglycerides increased[Ref]


Common (1% to 10%): Acute renal failure[Ref]


Common (1% to 10%): Polyuria[Ref]


Uncommon (0.1% to 1%): Pulmonary congestion

Frequency not reported: Dyspnea[Ref]


Uncommon (0.1% to 1%): Hypersensitivity[Ref]


1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Product Information. Cleviprex (clevidipine). The Medicines Company. 2008.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.