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Cleviprex Side Effects

Generic Name: clevidipine

Note: This document contains side effect information about clevidipine. Some of the dosage forms listed on this page may not apply to the brand name Cleviprex.

For the Consumer

Applies to clevidipine: intravenous emulsion

Along with its needed effects, clevidipine (the active ingredient contained in Cleviprex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:

More common


  • Chest pain or discomfort
  • difficult or labored breathing
  • pain or discomfort in the arms, jaw, back, or neck
  • shortness of breath
  • stopping of the heart
  • sweating
  • tightness in the chest
  • unconsciousness
  • very low blood pressure or pulse
  • vomiting
  • wheezing

For Healthcare Professionals

Applies to clevidipine: intravenous emulsion


Cardiovascular side effects have included atrial fibrillation (up to 21%), myocardial infarction (less than 1%), cardiac arrest (less than 1%), systemic hypotension, and reflex tachycardia. Hypotension and reflex tachycardia have been reported during postmarketing experience.[Ref]


Gastrointestinal side effects have included nausea (up to 21%) and vomiting (3.2%). Ileus and nausea have been reported during postmarketing experience.[Ref]


Renal side effects have included acute renal failure (up to 9%).[Ref]

Nervous system

Nervous system side effects have included headache (6.3%) and syncope (less than 1%).[Ref]


Respiratory side effects have included dyspnea (less than 1%).[Ref]


Other side effects have included decreased oxygen saturation (possible pulmonary shunting) during postmarketing experience.


Metabolic side effects have included increased blood triglycerides during postmarketing experience.


Hypersensitivity side effects have included hypersensitivity during postmarketing experience.


1. "Clevidipine (Cleviprex) for IV treatment of severe hypertension." Med Lett Drugs Ther 50 (2008): 73-4

2. "Product Information. Cleviprex (clevidipine)." The Medicines Company, Parsippany, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.