Benazepril Side Effects
Medically reviewed by Drugs.com. Last updated on Mar 23, 2025.
Applies to benazepril: oral tablet.
Important warnings
This medicine can cause some serious health issues
Oral route (tablet)
Discontinue benazepril hydrochloride as soon as possible when pregnancy is detected, as injury and death to the developing fetus may occur with use of drugs that act directly on the renin-angiotensin system.
Precautions
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.
You should not use this medicine together with sacubitril. Do not use this medicine and sacubitril/valsartan (Entresto®) within 36 hours of each other.
This medicine may cause serious types of allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
Call your doctor right away if you have severe stomach pain (with or without nausea or vomiting). This could be a symptom of a condition called intestinal angioedema.
Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, troubled breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.
Dizziness, lightheadedness, or fainting may also occur, especially when you get up suddenly from a lying or sitting position, or if you have been taking a diuretic (water pill). Do not drive or do anything else that could be dangerous until you or your child know how this medicine affects you. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, stop using this medicine and call your doctor right away.
Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea. These conditions may cause you to lose too much water or salt and may lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather.
Check with your doctor if you have a fever, chills, or sore throat. These may be symptoms of an infection caused by low white blood cells.
Hyperkalemia (high potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have the following symptoms: abdominal or stomach pain, confusion, difficulty breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, shortness of breath, or weakness or heaviness of the legs. Do not use medicines, supplements, or salt substitutes containing potassium without first checking with your doctor.
Check with your doctor right away if you have pain or tenderness in the upper stomach pain, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.
This medicine may be less effective in black patients. Black patients also have an increased risk of swelling of the hands, arms, face, mouth, or throat. Talk with your doctor if you have concerns about this.
Do not take other medicines unless they have been discussed with your doctor. This especially includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements, since they may tend to increase your blood pressure.
Common side effects of benazepril
Some side effects of benazepril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- headache
Less common side effects
- cough
- dizziness
- sleepiness or unusual drowsiness
Serious side effects of benazepril
Along with its needed effects, benazepril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking benazepril:
Less common side effects
- chills
- cold sweats
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
Incidence not known
- arm, back, or jaw pain
- blistering, peeling, or loosening of the skin
- bloating or swelling of the face, arms, hands, lower legs, or feet
- chest pain or discomfort
- diarrhea
- fast, irregular, pounding, or racing heartbeat or pulse
- feeling of warmth
- fever
- general feeling of tiredness or weakness
- itching
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- nausea
- rapid breathing
- rapid weight gain
- red skin lesions, often with a purple center
- red, irritated eyes
- redness of the face, neck, arms, and occasionally, upper chest
- skin rash
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- sweating
- tingling of the hands or feet
- unusual weight gain or loss
For healthcare professionals
Applies to benazepril: oral tablet.
General adverse events
The most common side effects were headache, dizziness, somnolence, and postural dizziness.[Ref]
Nervous system
- Common (1% to 10%): Headache, dizziness, somnolence, postural dizziness
- Frequency not reported: Hypertonia, paresthesia[Ref]
Hematologic
- Rare (less than 0.1%): Decreases in hemoglobin (a low value and a decrease of 5 g/dL)
- Frequency not reported: Thrombocytopenia, hemolytic anemia, eosinophilia[Ref]
Dermatologic
- Frequency not reported: Stevens-Johnson syndrome, pemphigus, dermatitis, pruritus, rash, photosensitivity, alopecia, sweating, angioedema[Ref]
Respiratory
Metabolic
- Frequency not reported: Uric acid increased, blood glucose increased, hyponatremia[Ref]
Cardiovascular
- Frequency not reported: Flushing, electrocardiographic changes, hypotension[Ref]
Gastrointestinal
- Frequency not reported: Nausea, pancreatitis, constipation, gastritis, vomiting, melena[Ref]
Genitourinary
Hepatic
- Frequency not reported: Serum bilirubin increased, liver enzymes increased[Ref]
Immunologic
- Frequency not reported: Infection[Ref]
Musculoskeletal
Other
- Frequency not reported: Fatigue, asthenia[Ref]
Psychiatric
- Frequency not reported: Anxiety, decreased libido, insomnia, nervousness[Ref]
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References
1. (2002) "Product Information. Lotensin (benazepril)." Ciba-Geigy Pharmaceuticals
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Further information
Benazepril side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.