Angiotensin II Side Effects
Medically reviewed by Drugs.com. Last updated on Jun 21, 2024.
Applies to angiotensin II: intravenous solution.
Precautions
It is very important that your doctor check your progress to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
This medicine may increase your risk of developing blood clots. Check with your doctor right away if you have swelling and pain in your arms, legs, or stomach, chest pain, shortness of breath, loss of sensation, confusion, or problems with muscle control or speech.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of angiotensin II
Along with its needed effects, angiotensin II may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking angiotensin II:
More common side effects
- black, tarry stools
- bleeding gums
- blood in the urine or stools
- confusion as to time, place, or person
- drowsiness
- fast, pounding, or irregular heartbeat or pulse
- headache
- nausea
- pain in the arms, legs, or lower back, especially in the calves or heels upon exertion
- pain, redness, or swelling in the arm or leg
- pinpoint red spots on the skin
- seeing, hearing, or feeling things that are not there
- troubled breathing
- unusual bleeding or bruising
- unusual excitement, nervousness, or restlessness
- unusual tiredness or weakness
- vomiting
Less common side effects
- blurred vision
- dry mouth
- flushed, dry skin
- fruit-like breath odor
- increased hunger
- increased thirst
- increased urination
- itching of the skin
- numbness and tingling of the face, fingers, or toes
- pale, bluish-colored, or cold hands or feet
- stomach pain
- sweating
- unexplained weight loss
Other side effects of angiotensin II
Some side effects of angiotensin II may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- itching in the genitals or other skin areas
- scaling
For healthcare professionals
Applies to angiotensin II: intravenous solution.
General adverse events
The most frequently reported side effects were thromboembolic events.[Ref]
Cardiovascular
- Very common (10% or more): Thromboembolic events (12.9%)
- Common (1% to 10%): Deep vein thrombosis, tachycardia, peripheral ischemia[Ref]
Hematologic
- Common (1% to 10%): Thrombocytopenia[Ref]
Metabolic
- Common (1% to 10%): Acidosis, hyperglycemia[Ref]
Psychiatric
- Common (1% to 10%): Delirium[Ref]
Other
- Common (1% to 10%): Fungal infection[Ref]
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References
1. (2022) "Product Information. Giapreza (angiotensin II)." La Jolla Pharmaceutical
More about angiotensin II
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- Drug class: vasopressors
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Further information
Angiotensin II side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.