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Amigesic Side Effects

Generic Name: salsalate

Note: This document contains side effect information about salsalate. Some of the dosage forms listed on this page may not apply to the brand name Amigesic.

For the Consumer

Applies to salsalate: oral tablets

Side effects include:

Tinnitus, nausea, hearing impairment, rash, vertigo.

For Healthcare Professionals

Applies to salsalate: oral capsule, oral tablet


The most frequently reported side effects were usually reversible and included tinnitus, nausea, hearing impairment, rash, and vertigo.[Ref]


Frequency not reported: Nausea, abdominal pain, diarrhea, gastrointestinal bleeding[Ref]


Frequency not reported: Hypotension[Ref]


Frequency not reported: Rash, angioedema, urticaria[Ref]


Frequency not reported: Hepatic function abnormal, hepatitis[Ref]


Frequency not reported: Nephritis[Ref]


Frequency not reported: Bronchospasm[Ref]


Frequency not reported: Tinnitus, hearing impaired, vertigo, creatinine clearance decreased[Ref]


Frequency not reported: Anaphylactic shock[Ref]


1. "Product Information. Salsalate (salsalate)." Amneal Pharmaceuticals, Glasgow, KY.

2. "Product Information. Disalcid (salsalate)." 3M Pharmaceuticals, St. Paul, MN.

3. Phillips BB, Joss JD, Mulhausen PL "Blood pressure elevation in a patient treated with salsalate." Ann Pharmacother 36 (2002): 624-7

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Amigesic (salsalate)

Consumer resources

Other brands: Disalcid, Salsitab

Professional resources

Related treatment guides