Ambien Side Effects
Generic Name: zolpidem
Note: This document contains side effect information about zolpidem. Some of the dosage forms listed on this page may not apply to the brand name Ambien.
Common side effects of Ambien include: dizziness. Other side effects include: hallucination. See below for a comprehensive list of adverse effects.
For the Consumer
For Healthcare Professionals
Applies to zolpidem: oral spray, oral tablet, oral tablet extended release, sublingual tablet
There is evidence of a dose relationship for adverse effects, particularly for certain central nervous system and gastrointestinal events and in the elderly; in theory, these adverse effects should be less if this drug is taken immediately before bedtime.
Very common (10% or more): Headache (up to 19%), somnolence/drowsiness (up to 15%), dizziness (up to 12%)
Common (1% to 10%): Lethargy, lightheadedness, ataxia, vertigo, labyrinthitis, balance disorder, attention disturbance, hypoesthesia, ataxia, burning sensation, paresthesia, postural dizziness, tremor
Common (1% to 10%): Palpitations, increased blood pressure
Rare (less than 0.1%): Flushing, hypotension, hot flashes, angina pectoris, arrhythmia, arteritis, circulatory failure, extrasystoles, aggravated hypertension, myocardial infarction, phlebitis, varicose veins, ventricular tachycardia[Ref]
Common (1% to 10%): Rash, urticaria, skin wrinkling
Common (1% to 10%): Diarrhea, dry mouth, abdominal pain, constipation, dyspepsia, hiccup, nausea, vomiting, gastroenteritis, abdominal discomfort, abdominal tenderness, frequent bowel movements, gastroesophageal reflux disease, flatulence
Common (1% to 10%): Allergy
Rare (less than 0.1%): Allergic reaction, aggravated allergy, anaphylactic shock
Common (1% to 10%): Appetite disorder
Uncommon (0.1% to 1%): Anorexia, hyperglycemia, thirst
Common (1% to 10%): Back pain, arthralgia, myalgia, neck pain, muscle cramp
Uncommon (0.1% to 1%): Leg cramps, arthritis, muscle spasms, involuntary muscle contractions
Common (1% to 10%): Diplopia, abnormal vision, visual disturbance, eye redness, blurred vision, altered visual depth perception, asthenopia
Uncommon (0.1% to 1%): Eye irritation, eye pain, scleritis
Uncommon (0.1% to 1%): Pallor, pain, edema, falling, malaise, trauma, taste perversion
Frequency not reported: Injuries (e.g., hip fractures, intracranial hemorrhages)[Ref]
Common (1% to 10%): Depression, abnormal dreams, sleep disorder, insomnia, exacerbated/aggravated insomnia, hallucinations, agitation, nightmare, drugged feeling, confusion, euphoria, memory impairment, amnesia, anterograde amnesia, nervousness, disorientation, anxiety, psychomotor retardation, binge eating, depersonalization, disinhibition, mood swings, stress symptoms, apathy
Uncommon (0.1% to 1%): Decreased cognition, detached, difficulty concentrating, emotional lability, illusion, sleeping (after daytime dosing), irritability, drunk feeling, reduced alertness
Rare (less than 0.1%): Impotence, abnormal thinking, aggressive reaction, decreased libido, delusion, dementia, feeling strange, hysteria, intoxicated feeling, manic reaction, panic attacks, personality disorder, somnambulism, suicide attempts, neurosis, perceptual disturbances, restlessness, libido disorder, rages, inappropriate behavior
Frequency not reported: Psychoses, dependence
Postmarketing reports: Anger, abnormal behavior[Ref]
Common (1% to 10%): Sinusitis, pharyngitis, upper respiratory infection, lower respiratory infection, throat irritation, nasopharyngitis, dry throat, rhinitis
Uncommon (0.1% to 1%): Bronchitis, coughing, dyspnea
Uncommon (0.1% to 1%): Abnormal hepatic function, increased ALT/SGPT
Rare (less than 0.1%): Bilirubinemia, increased AST/SGOT
Rare (less than 0.1%): Acute renal failure, renal pain[Ref]
Postmarketing reports: Sublingual application site reactions (e.g., oral ulcers, blisters, mucosal inflammation)[Ref]
1. "Product Information. Zolpimist (zolpidem)." Magna Pharmaceuticals Inc, Louisville, KY.
2. "Product Information. Edluar (zolpidem)." Meda Pharmaceuticals, Somerset, NJ.
3. "Product Information. Ambien (zolpidem)." sanofi-aventis, Bridgewater, NJ.
4. "Product Information. Ambien CR (zolpidem)." Sanofi-Synthelabo Inc, New York, NY.
5. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
6. "Product Information. Intermezzo (zolpidem)." Purdue Pharma LP, Stamford, CT.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about Ambien (zolpidem)
- Ambien Side Effects
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- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- FDA Alerts (4)