Aceon Side Effects
Generic name: perindopril
Medically reviewed by Drugs.com. Last updated on Feb 22, 2023.
Note: This document contains side effect information about perindopril. Some dosage forms listed on this page may not apply to the brand name Aceon.
Summary
Common side effects of Aceon include: cough. Continue reading for a comprehensive list of adverse effects.
Applies to perindopril: oral tablets.
Warning
Side effects include:
Cough, proteinuria, palpitation, sinusitis, viral infection, dyspepsia, fever, upper extremity pain, hypertonia.
Dizziness reported at a rate similar to that with placebo, but incidence increases with increased dosage, suggesting causal relation to the drug.
For Healthcare Professionals
Applies to perindopril: oral tablet.
General
The most common adverse events were cough, dizziness, and back pain.[Ref]
Respiratory
Very common (10% or more): Cough (up to 12%)
Common (1% to 10%): Dyspnea, epistaxis
Uncommon (0.1% to 1%): Bronchospasm
Very rare (less than 0.01%): Eosinophilic pneumonia, rhinitis[Ref]
Nervous system
Common (1% to 10%): Dizziness, headache, paresthesia, vertigo, tinnitus, dysgeusia, drowsiness
Uncommon (0.1% to 1%): Somnolence, syncope
Very rare (less than 0.01%): Stroke[Ref]
Gastrointestinal
Common (1% to 10%): Abdominal pain, constipation, diarrhea, dyspepsia, nausea, vomiting
Uncommon (0.1% to 1%): Dry mouth
Very rare (less than 0.01%): Pancreatitis
Postmarketing reports: Acute pancreatitis[Ref]
Cardiovascular
Common (1% to 10%): Hypotension, palpitations, vasculitis, flushing, impaired peripheral circulation
Uncommon (0.1% to 1%): Tachycardia
Rare (0.01% to 0.1%): Sudden cardiac arrest
Very rare (less than 0.01%): Angina pectoris, arrhythmia, myocardial infarction[Ref]
Dermatologic
Common (1% to 10%): Pruritus, rash
Uncommon (0.1% to 1%): Urticaria, angioedema, photosensitivity reactions, pemphigoid, hyperhidrosis, eczema, sweating
Very rare (less than 0.01%): Erythema multiforme
Postmarketing reports: Bullous pemphigoid, pemphigus, psoriasis, exfoliative dermatitis[Ref]
Other
Common (1% to 10%): Asthenia, discomfort on exertion
Uncommon (0.1% to 1%): Chest pain, malaise, edema peripheral, pyrexia, fall, atypical chest pain
Postmarketing reports: Serositis[Ref]
Musculoskeletal
Common (1% to 10%): Muscle cramps, back pain
Uncommon (0.1% to 1%): Arthralgia, myalgia[Ref]
Hepatic
Common (1% to 10%): ALT increased
Uncommon (0.1% to 1%): AST increased
Rare (0.01% to 0.1%): Blood bilirubin increased, hepatic enzyme increased
Very rare (less than 0.01%): Hepatitis
Postmarketing reports: Hepatic failure, jaundice[Ref]
Ocular
Common (1% to 10%): Visual disturbances[Ref]
Renal
Uncommon (0.1% to 1%): Renal insufficiency, blood urea increased, blood creatinine increased
Very rare (less than 0.01%): Acute renal failure
Postmarketing reports: Nephritis[Ref]
Metabolic
Uncommon (0.1% to 1%): Hypoglycemia, hyperkalemia, hyponatremia
Postmarketing reports: Symptomatic hyponatremia[Ref]
Hematologic
Uncommon (0.1% to 1%): Eosinophilia, leukopenia/neutropenia
Very rare (less than 0.01%): Agranulocytosis or pancytopenia, hemoglobin decreased and hematocrit decreased, hemolytic anemia in patients with a congenital deficiency of glucose-6-phosphate dehydrogenase, thrombocytopenia, unexplained change in prothrombin ratio
Postmarketing reports: Anemia, leukocytosis, elevated erythrocyte sedimentation rate[Ref]
Psychiatric
Uncommon (0.1% to 1%): Mood disturbances, sleep disorder
Very rare (less than 0.01%): Confusion, depression, hallucinations[Ref]
Genitourinary
Uncommon (0.1% to 1%): Erectile dysfunction[Ref]
Immunologic
Postmarketing reports: Positive antinuclear antibody[Ref]
More about Aceon (perindopril)
- Check interactions
- Compare alternatives
- Drug images
- Dosage information
- During pregnancy
- Drug class: Angiotensin Converting Enzyme Inhibitors
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Patient resources
Professional resources
Related treatment guides
References
1. "Product Information. Aceon (perindopril)." Solvay Pharmaceuticals Inc (2001):
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.