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Emend 3-Day

Generic Name: aprepitant (a PREP i tant)
Brand Name: Emend, Emend 2-Day, Emend 3-Day

Medically reviewed: August 3, 2017

What is Emend 3-Day?

Emend 3-Day blocks the actions of chemicals in the body that trigger nausea and vomiting.

Emend 3-Day is used in adults and children to prevent nausea and vomiting caused by cancer chemotherapy. This medicine is also used (only in adults) to prevent nausea and vomiting that may be caused by surgery.

Emend 3-Day is given ahead of time and will not treat nausea or vomiting that you already have.

Emend 3-Day capsules are for use in adults and children who are at least 12 years old. This medicine oral suspension (liquid) can be given to adults and children as young as 6 months old.

Emend 3-Day may also be used for purposes not listed in this medication guide.

Important Information

You should not take Emend 3-Day if you also take pimozide. A serious drug interaction can occur when pimozide is used together with this medicine.

Before taking this medicine

You should not use Emend 3-Day if you are allergic to it, or if you take another medicine called pimozide (Orap). This medicine can cause unwanted or dangerous effects when used with pimozide.

To make sure Emend 3-Day is safe for you, tell your doctor if you have:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Emend 3-Day can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy, and for 1 month after your last dose.

It is not known whether Emend 3-Day passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Emend 3-Day?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Emend 3-Day is not for long-term use. For use in chemotherapy, you will most likely need only 3 separate doses. When used before surgery, you will likely receive only 1 dose.

The first dose of Emend 3-Day is usually taken 1 hour before treatment with chemotherapy, or 3 hours before a surgery. Follow your doctor's dosing instructions very carefully.

You may also be given other medicines with Emend 3-Day to further help prevent nausea and vomiting.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Emend 3-Day can be taken with or without food. If you take this medicine before surgery, follow your doctor's instructions about any restrictions on food or beverages.

Do not crush, chew, break, or open an Emend 3-Day capsule. Swallow it whole.

Give the oral suspension (liquid) using only the dosing syringe provided.

Do not share this medicine with another person. Emend 3-Day should not be used to treat general nausea that is unrelated to chemotherapy or surgery.

If you also take warfarin (Coumadin, Jantoven), you may need extra "INR" or prothrombin time tests after you have taken Emend 3-Day.

Store Emend 3-Day capsules at room temperature away from moisture and heat.

Store the prefilled liquid dosing syringe in the refrigerator, do not freeze. After taking the liquid out of the refrigerator, you must use it within 3 hours.

Throw away any liquid medicine not used within 3 days (72 hours) after you received it. Do not save it for later use.

What happens if I miss a dose?

Call your doctor for instructions if you forget to take your medicine within the prescribed length of time before your chemotherapy or surgery.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Emend 3-Day?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Emend 3-Day side effects

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching, skin sores or peeling; warmth or tingly feeling; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • low blood cell counts--fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding; or

  • dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Emend 3-Day?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can interact with Emend 3-Day. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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