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NK1 receptor antagonists

What are NK1 receptor antagonists?

Neurokinin-1 (NK1) receptor antagonists are used for prevention of acute and delayed nausea and vomiting. The NK1 receptor antagonist competitively binds to the NK1 receptor, which blocks the binding of substance P and prevents the emetic signal being transmitted. NK1 receptor antagonists can be used in conjunction with 5-HT3-receptor antagonists and corticosteroids to augment their antiemetic activity.

List of NK1 receptor antagonists:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Emend (Pro)
Generic name: aprepitant
8.1
16 reviews
Varubi (Pro)
Generic name: rolapitant
10
1 review
Emend for Injection (Pro)
Generic name: fosaprepitant
No reviews
Cinvanti (Pro)
Generic name: aprepitant
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with NK1 receptor antagonists:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.