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Emend for Injection

Generic Name: fosaprepitant (FOS a PREP i tan t)
Brand Name: Emend for Injection

Medically reviewed on April 25, 2018

What is Emend for Injection?

Emend for Injection blocks the actions of chemicals in the body that trigger nausea and vomiting.

Emend for Injection is used together with other medications to prevent nausea and vomiting that may be caused by chemotherapy in adults and children who are at least 6 months old.

Emend for Injection is given ahead of time and will not treat nausea or vomiting that you already have.

Emend for Injection may also be used for purposes not listed in this medication guide.

Important Information

You should not use Emend for Injection if you also take pimozide. Using these drugs together can cause unwanted or dangerous effects.

Before taking this medicine

You should not be treated with Emend for Injection if you are allergic to it, or if you take another medicine called pimozide (Orap). This medicine can cause unwanted or dangerous effects when used with pimozide.

To make sure Emend for Injection is safe for you, tell your doctor if you have:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

Emend for Injection can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy for at least 1 month after each dose of this medicine.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How is fosaprepitant given?

Emend for Injection is given as an infusion into a vein. A healthcare provider will give you this injection.

The first dose of Emend for Injection is usually given before your chemotherapy treatment begins.

You may also be given other medicines, including aprepitant capsules (Emend), to further help prevent nausea and vomiting.

Emend for Injection is not for long-term use.

If you also take warfarin (Coumadin, Jantoven), you may need extra "INR" or prothrombin time tests after you have received Emend for Injection.

What happens if I miss a dose?

Since Emend for Injection injection is given only once on the first day of your chemotherapy treatment, you are not likely to be on a dosing schedule.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Emend for Injection?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Emend for Injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives, rash, itching, skin sores or peeling; warmth or tingly feeling; fast or weak heartbeats, severe dizziness; trouble breathing or swallowing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain, redness, swelling, or bruising where the medicine was injected;

  • a light-headed feeling, like you might pass out;

  • pain or burning when you urinate; or

  • low blood cell counts--fever, swollen gums, mouth sores, skin sores, cold or flu symptoms, pale skin, easy bruising, unusual bleeding.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Emend for Injection?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect Emend for Injection. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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