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Aimovig SureClick Autoinjector

Generic name: erenumabe-REN-ue-mab ]
Drug class: CGRP inhibitors

Medically reviewed by on Nov 13, 2022. Written by Cerner Multum.

What is Aimovig SureClick Autoinjector?

Aimovig SureClick Autoinjector is used to prevent migraine headaches in adults.

Aimovig SureClick Autoinjector may also be used for purposes not listed in this medication guide.

Aimovig SureClick Autoinjector side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Aimovig SureClick Autoinjector may cause serious side effects. Call your doctor at once if you have:

Common side effects of Aimovig SureClick Autoinjector may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use Aimovig SureClick Autoinjector if you are allergic to it.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Aimovig SureClick Autoinjector will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as preeclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby.

Ask a doctor if it is safe to breastfeed while using Aimovig SureClick Autoinjector.

How should I use Aimovig SureClick Autoinjector?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Aimovig SureClick Autoinjector is injected under the skin, usually once per month. A healthcare provider may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Prepare your injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine.

Each prefilled syringe or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside.

Do not shake the syringe or autoinjector or you may ruin the medicine.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes.

Store Aimovig SureClick Autoinjector in its original carton in the refrigerator, away from heat and light. Do not freeze.

Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Protect from sunlight. Do not heat the medicine in hot water or in a microwave.

You may store the medicine for up to 7 days at room temperature.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then go back to your regular injection schedule. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Aimovig SureClick Autoinjector?

Avoid injecting Aimovig SureClick Autoinjector into skin that is red, bruised, tender, or hard.

What other drugs will affect Aimovig SureClick Autoinjector?

Other drugs may affect Aimovig SureClick Autoinjector, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Popular FAQ

Ajovy and Aimovig are both calcitonin gene-related peptide (CGRP) inhibitors used for migraine prevention in adults. The dosing, side effects, effectiveness and costs of these medicines can vary. As demonstrated in studies, these agents can reduce the number of migraine headache days you experience by about 1.5 to 3 days per month when compared to a placebo (inactive) treatment, but your response may vary. Continue reading

The gastrointestinal (digestive) tract contains CGRP proteins. Some studies suggest that CGRP may play an important role in maintaining the movement of the bowels. Blocking intestinal CGRP with a CGRP antagonist such as Aimovig (erenumab-aooe), a medicine used for migraine prevention, may lead to constipation, which can be severe in some patients. Continue reading

It takes approximately 154 days (22 weeks, or over 5 months) for Aimovig to be eliminated out of your system. Aimovig is a prescription medicine injected monthly for the preventive treatment of migraine in adults. Continue reading

Aimovig (erenumab-aooe) works by blocking the calcitonin gene-related peptide (CGRP) receptor binding site and function. This helps to prevent the development of a migraine headache and associated pain. CGRP is a protein thought to cause blood vessels to dilate and lead to inflammation and migraine headache pain. Continue reading

There is not a specific warning against alcohol (ethanol) consumption with the migraine preventive medicine Aimovig (erenumab-aooe). However, drinking alcoholic beverages can trigger a migraine headache in many people, or may worsen a headache. It may be best to avoid alcohol if you take Aimovig and fall into these categories. Continue reading

Aimovig (erenumab-aooe), a medicine used for migraine prevention, did not lead to hair loss (alopecia) during clinical trials submitted for FDA-approval. Alopecia has been reported as a possible side effect in post-marketing reports of Aimovig. Continue reading

The Aimovig autoinjector is a medical device that contains one prefilled dose of medicine in a spring-loaded syringe. You, or your caregiver, can learn to give this medicine at home. Many patients prefer an autoinjector over a syringe as they are easier to use and may cause less worry. Aimovig is a medicine used one time per month to help prevent migraine headaches. Continue reading

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.