How quickly does Mavenclad work?
Studies evaluating the use of Mavenclad (generic name: cladribine) for multiple sclerosis (MS) found a reduction in MS relapses (flare-ups) over about a two year period. A relapse is a period of time when MS symptoms get worse.
- Over 96 weeks, 81% of patients who took Mavenclad were relapse-free compared to 63% of those who took a placebo.
- Mavenclad also decreased 3-month progression of disability (worsening) due to MS when compared to a placebo.
- It also significantly reduced the median number of MRI lesions when compared to a placebo at 96 weeks.
In the clinical trial program of Mavenclad in MS, the mean time in the study (including follow-up) was almost 5 years, and roughly one-quarter of patients who received treatment had 8 years of time in the study, including follow-up.
Mavenclad works over the long-term, but for most patients, the active ingredient in Mavenclad does not remain in the body beyond one week after administration. However, long-term safety concerns exist with Mavenclad, and you should discuss these with your doctor before starting treatment.
This is not all the information you need to know about Mavenclad (generic name: cladribine) for safe and effective use. Review the full Mavenclad information here, and discuss this information with your doctor or other health care provider.
References
- Mavenclad (cladribine). Product Label. EMD Serono, Inc. Rockland, MA. April 2019. Accessed August 12, 2020 at https://www.emdserono.com/us-en/pi/mavenclad-pi.pdf
- EMD Serono. Mavenclad website. Accessed August 12, 2020 at https://www.mavenclad.com
- Dosing Guide. Mavenclad (cladribine) Tablets. EMD Serono. April 2019. Accessed August 12, 2020 at https://www.mavenclad.com/content/dam/web/healthcare/neurology/united-states/pdfs/MAVENCLAD_Dosing_Guide_4.29.pdf
Read next
What are 8 key Mavenclad side effects to watch out for?
8 key side effects with Mavenclad use include a risk of cancer, birth defects in an unborn baby, a severe brain infection called PML, liver toxicity, other types of infections like shingles, tuberculosis or hepatitis, allergic reactions, heart failure and low white blood cell counts. Continue reading
How effective is Mavenclad for MS?
In the study, Mavenclad significantly decreased the number of relapses (the primary endpoint of the study) when compared to a placebo (an inactive treatment). Over the 96 weeks, 81% of patients who took Mavenclad were relapse-free compared to 63% of those who took a placebo. Continue reading
Is Mavenclad a chemotherapy drug?
No, Mavenclad is not a chemotherapy (cancer) drug. It is an oral purine antimetabolite approved for the treatment of relapsing forms of multiple sclerosis (MS), to include relapsing-remitting disease and active secondary progressive disease, in adults. Mavenclad tablets are taken by mouth and are given as two yearly treatment courses. Continue reading
Related medical questions
- Does Mavenclad have a Black Box Warning?
- Does Mavenclad cause hair loss?
- Does Mavenclad cause weight gain?
- How is Mavenclad given/administered?
- What are the new drugs used for multiple sclerosis (MS)?
- How long can you live with multiple sclerosis?
- What are the early warning signs of Multiple Sclerosis?
- How do you test for multiple sclerosis?
- What are the early signs of multiple sclerosis?
- Prednisone: What are 12 Things You Should Know?
- Prednisone vs Prednisolone - What's the difference?
- Is Kesimpta better than Ocrevus?
- What are 8 key Kesimpta side effects to watch out for?
- How much does Ocrevus cost?
- Briumvi vs Ocrevus: How do they compare?
- Who is the actress in the Kesimpta commercial?
- How long does it take Ocrevus to work?
- Is Tecfidera an immunosuppressant?
- How do Vumerity and Tecfidera compare for multiple sclerosis (MS)?
- Can I stop taking Tecfidera? What happens if I do?
- Ocrevus side effects: What are 5 key side effects to watch for?
- How long does an Ocrevus infusion take?
- Is Ocrevus a form of chemotherapy?
- What causes flushing with Tecfidera?
- Can you drink alcohol while taking Tecfidera?
- How long can Kesimpta be out of the fridge?
- Where and how should Copaxone be injected?
- Does Tysabri suppress the immune system?
- How long does it take for Kesimpta to work?
- How does Ocrevus work for MS?
Drug information
Related support groups
- Mavenclad (9 questions, 3 members)
- Cladribine (5 questions, 10 members)
- Multiple Sclerosis (98 questions, 557 members)