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Is Invokana the same as metformin?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Sep 11, 2024.

Official Answer by Drugs.com

Is Invokana better than metformin? Can you take Invokana with metformin?

No, Invokana is not the same medicine as metformin. Invokana and metformin both are medicines that treat type 2 diabetes by lowering blood glucose levels, but they work in different ways.

How does metformin work?

Metformin is belongs to the medicine class of non-sulfonylureas, and works in three ways to reduce blood sugar levels by:

How does Invokana work?

Invokana (canagliflozin) reduces blood sugar levels by inhibiting a protein in the kidney called SGLT2 (Sodium-glucose co-transporter 2) which usually reabsorbs sugar back into the bloodstream. This means that Invokana:

Related questions

Is Invokana better than metformin?

Neither of the medications are better than the other. Different diabetes medicines will suit different patients, depending on the individual medical situation. It is up to the prescriber to decide which medication will be most beneficial to their individual patients.
The prescriber will usually take into account:


Can I take Invokana with metformin?

Yes, you can take Invokana with metformin. Your health care provider may prescribe metformin and Invokana as the two separate medicines that you take separately. It may also be prescribed as the combination medication Invokamet or Invokamet CR, which contains both metformin and Invokana in one tablet.

Often only one diabetic medication is necessary to treat diabetes and therefore metformin, Invokana or another type of diabetic medication is taken on its own.

References

Read next

Why does metformin cause diarrhea?

According to the manufacturer, about 53% of people taking metformin immediate-release tablets experienced diarrhea in one clinical study. In another study, 10% of people taking metformin extended-release tablets reported diarrhea as a side effect. Continue reading

Can you take metformin without food?

If you take metformin without food you may end up with an upset stomach, especially if you are just starting treatment. Nausea and vomiting is one of the most common side effects with metformin and can occur in over a quarter of patients. Continue reading

Does metformin lower A1C, if so how much?

When metformin is used alone as monotherapy, it lowers A1C by about 1% to 2% on average. A1C is a measure of longer-term blood sugar control. In most patients, metformin is suggested as the initial treatment for type 2 diabetes, but its glucose-lowering effect may not be adequate for all patients if used alone. Continue reading

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