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What drugs are contained in HIV treatment Juluca?

Medically reviewed by Judith Stewart, BPharm. Last updated on May 16, 2025.

Official Answer by Drugs.com

Juluca is a single-tablet, two-drug regimen of dolutegravir (Tivicay) and rilpivirine (Edurant) for the treatment of human immunodeficiency virus type 1 (HIV-1) infection.

Juluca is used in the treatment patients with virologically suppressed HIV-1 infection ((HIV-1 RNA less than 50 copies per mL) who have been on a stable medication regimen for at least six months, with no record of treatment failure and no resistance to the components of Juluca.

Juluca tablets are taken once daily with a meal.

Serious side effects include skin rash and allergic reactions, liver problems and depression or mood changes. Common side effects include diarrhea and headache.

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