What drugs are contained in HIV treatment Juluca?
Juluca is a single-tablet, two-drug regimen of dolutegravir (Tivicay) and rilpivirine (Edurant) for the treatment of human immunodeficiency virus type 1 (HIV-1) infection.
- Dolutegravir is a HIV-1 integrase strand transfer inhibitor (INSTI).
Dolutegravir is contained in Tivicay (dolutegravir), Dovato (dolutegravir and lamivudine), and Triumeq (abacavir, dolutegravir and lamivudine). - Rilpivirine is a HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI).
Rilpivirine is contained in Edurant (rilpivirine), Complera (emtricitabine, rilpivirine and tenofovir disoproxil fumarate), Odefsey (emtricitabine, rilpivirine and tenofovir alafenamide), and Cabenuva (cabotegravir and rilpivirine).
Juluca is used in the treatment patients with virologically suppressed HIV-1 infection ((HIV-1 RNA less than 50 copies per mL) who have been on a stable medication regimen for at least six months, with no record of treatment failure and no resistance to the components of Juluca.
Juluca tablets are taken once daily with a meal.
Serious side effects include skin rash and allergic reactions, liver problems and depression or mood changes. Common side effects include diarrhea and headache.
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Can Descovy be used for pre-exposure prophylaxis (PrEP) in HIV?
Yes. The FDA approved Descovy (emtricitabine and tenofovir alafenamide) for pre-exposure prophylaxis (PrEP) in October 2019 to help reduce the risk of HIV-1 infection. Continue reading
Which medicines should not be taken with Biktarvy?
- Biktarvy is a complete regimen and use with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
- Biktarvy is associated with many drug interactions as it contains three different medicines, increasing your risk for interactions. Have your health care provider check for possible interactions with other prescription medicines, OTCs or herbal you take.
- You should not take Biktarvy with dofetilide (Tikosyn), a drug used for heart rhythm disorders or rifampin (Rifadin), a medicine for tuberculosis (TB). These drugs are contraindicated with the use of Biktarvy.
Who are the actors in the Dovato commercial?
Three real-life patients feature in the Dovato commercial “Detect This” released on May 23, 2022. They are Jovon [surname withheld], Ann Edwards, and Armando [surname withheld]. Continue reading
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