Skip to main content

Is Adzenys XR-ODT the same as Adderall XR?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Feb 26, 2025.

Official answer

by Drugs.com

No, Adzenys XR-ODT is the first extended-release orally disintegrating amphetamine tablet approved by the FDA after it was established that it was bioequivalent to Adderall XR (mixed amphetamine salts extended-release capsule). Adzenys XR-ODT is a patented formulation and not a generic of Adderall XR. Adzenys XR-ODT is a mixture of immediate-release and polymer-coated, delayed-release resin particles.

Orally disintegrating tablets are formulated to dissolve in the mouth, rather than being swallowed whole like tablets or capsules. Extended-release tablets release the active drug throughout the day. Adzenys XR-ODT dissolves quickly in the mouth and can be taken without water.

What is Adzenys XR-ODT?

Once-daily Adzenys XR-ODT (generic name: amphetamine) is a central nervous system (CNS) stimulant indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in patients 6 years and older.

Adzenys XR-ODT may help improve attention and reduce impulsivity and hyperactivity in patients with ADHD.

The most common side effects reported with Adzenys XR-ODT are:

  • dry mouth (xerostomia)
  • loss of appetite
  • trouble sleeping (insomnia)
  • nervousness
  • mood changes
  • headache
  • weight loss
  • nausea
  • stomach pain
  • fever

This is not all of the side effects reported with Adzenys XR-ODT. You can review a full listing of side effects and warnings found in the FDA-approved Medication Guide for Adzenys XR-ODT.

Related questions

How does Adzenys XR-ODT come at the pharmacy?

Adzenys XR-ODT comes in six different orally disintegrating tablet strengths in blister packs (3.1, 6.3, 9.4, 12.5, 15.7, and 18.8 mg). This enables your doctor to individualize a specific dose for you or your child. It is usually taken once a day in the morning, but your doctor will tell you the correct dose and schedule.

Adzenys XR-ODT is a Schedule II controlled substance (CII) because it may be abused or lead to addiction. Keep it in a safe place to prevent misuse and abuse. Selling or giving away this drug may harm others and is against the law.

This is not all the information you need to know about Adzenys XR-ODT (amphetamine) for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full Adzenys XR-ODT information here, and discuss this information and any questions you have with your doctor or other health care provider.

References

Read next

How long does Adderall last in your system?

When taken as prescribed, the effects of Adderall last for about 4 to 6 hours. The effects of Adderall XR last for up to 12 hours because this brand of Adderall is designed for slow and sustained release. Continue reading

Modafinil (Provigil) vs Adderall: What's the difference?

Modafinil and Adderall are both classified as CNS stimulants but have different chemical structures, which means there are differences in their addiction potential and risk of side effects. Modafinil and Adderall both have stimulant-type effects, but modafinil is a much milder stimulant than Adderall.

Continue reading

How long does Adderall withdrawal last?

It is difficult to say exactly how long Adderall withdrawal lasts because it depends on the person and the process is different for everyone. Some people’s withdrawal symptoms may resolve in as little as 5 days, others may still be experiencing symptoms 4 weeks later or even longer. People who have taken Adderall for a long time at a high dose should expect withdrawal symptoms to last longer, sometimes several months. Continue reading

Related medical questions

Drug information

Related support groups

Medical Disclaimer